David Mick

Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase. www.nature.com/articles/s41...

Are conference fees holding you back? 🧪 We have a flexible system of financial assistance – including fee waivers & travel grants – to support young scientists, especially those from underrepresented regions. Learn more about the wide range of fellowships offered. https://s.embl.org/grants

A new Science study shows that bumble bees can position a ball underneath a fake “flower” to reach a reward, suggesting they can exhibit spontaneous problem-solving and challenging the notion that such advanced cognitive abilities are exclusive to large-brained vertebrates. https://scim.ag/4vs08dC

We are very proud of our @uni-saarland.de B.Sc. student Smilla @smillakoy.bsky.social for winning the Euro #Cilia2027 image competition. A well-deserved recognition of her amazing work. We're lucky to have such talent in the lab!

I am hoping that all companies who are selling antibodies will take this very seriously.

Please check this out! Great technical improvement. Congrats Bas and Helge!

Had a fantastic visit at our friends at the IFIB @unituebingen.bsky.social, where I presented our iAPEX technology and how we use it to study primary cilia dynamics. @for5547.bsky.social Fun discussion with the #biochemistry M.Sc. students after the talk and a lovely dinner. Thanks for the invite!

Finally got around to reading this fantastic work on in vitro reconstitution of plasmodium #microtubules, highlighting the importance of lattice interactions. Congrats all! It was a fun read.

Also our froggies had a fantastic time at our @for5547.bsky.social retreat on primary #cilia dynamics. This one was amazed about all the discussions and progress in each single project. So many potential new research directions. Go team #xenopus! @walenteklab.bsky.social @kerstinfeistel.bsky.social

Great start of @for5547.bsky.social PI retreat with primary #cilia and 🌞😎

Exciting to see this out in its final form! Wonderful work led by @probablycarmen.bsky.social. Want to know why protrusions are better at initiating immune signaling in #Tcells? Look no further. Link to Carmen’s 🧵 on the preprint bsky.app/profile/prob...

We'll be back for our @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social 56th e-symposium August 25th 2026- register: www.eventbrite.co.uk/e/bscb-genso... Sign-up to speak: forms.gle/yNtr4AKpXowD... #UKCilia2026 /fin

Great lineup again at the DGZ Focus Workshop tomorrow. Can't wait!

The 2026 Otto Warburg Medal winner Maya Schuldiner received the medal from @volkerhaucke-lab.bsky.social after a moving laudatio by Christian Ungermann Thanks to @elsevierconnect.bsky.social for the continuous support!

SAVE THE DATE - our next DGZ International Meeting will take place March 14-17,2027, in Bonn, Germany. Stay tuned!

𝗠𝗲𝗲𝘁 𝗼𝘂𝗿 𝗸𝗲𝘆𝗻𝗼𝘁𝗲 𝘀𝗽𝗲𝗮𝗸𝗲𝗿𝘀 𝗳𝗼𝗿 #𝗖𝗶𝗹𝗶𝗮𝟮𝟬𝟮𝟳! We are grateful for their participation and look forward to welcoming the cilia community on 8-12, March 2027. Wishing you all a happy and inspiring 2026! 🎉 #Cilia #Milan

Another fantastic technology development paper by @davidbreslowlab.bsky.social. Being able to perform microscopy-based CRISPR screens on fixed cells is big. And TZMP1 is a fascinating transition zone proteins. We may be missing many more of these #microproteins. Congrats to all authors!

"... the species of trees we choose to nurture may be just as important as the number of trees we plant." Read the blog post behind the paper by Yao et al. regarding the role of #tree species in the #climate impact of European #forests. communities.springernature.com/posts/rethin...

Amazing work by the Breslow lab. Super excited to finally see this published. Unbiased CRISPRa screening reveals a novel and unexpected cilia disassembly pathway associated with neurological disease (focal cortical dysplasia). Must read for both #cilia and screening technology enthusiasts.

It was a lot of fun to write this review on cilia proteimics with Bernhard Schermer @cilib.social.cologne.ap.brid.gy and Ronald Ropeman, and we are excited to see it published in the @jcellsci.bsky.social special issue on Cilia and Flagella: from basic Biology to Disease.

Interesting connection between primary #cilia and energy #metabolism in #mitochondria. www.biorxiv.org/content/10.1...

Very much looking forward to our next focus workshop on #cilia and #centrosomes. We'll have fantastic speakers again.

With deep sadness, we share that Prof. Jochen Guck, Director at the Max Planck Institute for the Science of Light passed away on October 3. His visionary work bridged physics and medicine. We have lost a brilliant scientist and dear friend. mpl.mpg.de/news/article... @fau.de 📸 Stephan Spangenberg

New findings in mice cast light on the pathways behind the growth of painful bone tumors in hereditary multiple osteochondroma and suggest that these mechanisms could be targeted to slow the disease’s progression. Learn more in #ScienceSignaling: https://scim.ag/46VRSIp

We’re renewing our collaboration with Google DeepMind! We'll keep developing the AlphaFold Database to support protein science worldwide 🎉 To mark the moment we’ve synchronised the database with UniProtKB release 2025_03. www.ebi.ac.uk/about/news/t... 🖥️🧬 #AlphaFold @pdbeurope.bsky.social

Today is the #BBSGlobalDay — an opportunity to raise awareness of this rare condition and offer support to everyone living with BBS and their loved ones 🌍 🌎 🌏 www.img.cas.cz/2025/10/8758...

First pizza lunch after a whirlwind week moving into our brand-new research building. Exhausted, but absolutely thrilled by the incredible facilities & lab space. Can’t wait to dive back into science. A few benches are still waiting for curious minds: PhD students and postdocs, come join us! 😉

'This story shows that it is possible to establish a multibillion-dollar industry purely by letting scientists communicate their research, exchange information and share materials.' www.nature.com/articles/d41...

Science doesn’t need to be pretty and go according to plan; it just needs to lead to a discovery. If doesn’t have to be done alone or together with someone else; there just needs to be a discovery. It doesn’t need to happen fast or slow; just as long as there’s a discovery, then everybody is happy.

EMBL Cell Biology and Biophysics department is searching for a new director. A major position to lead this field in Europe and beyond. embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

SNAP-tag is a widespread tool for labelling protein for bioimaging. An article published in Nature Chemical Biology presents SNAP-tag2 with increased labelling kinetics and brightness, which translates into a better performance in live-cell super-resolution imaging. go.nature.com/46fMIZd 🧪

Beautiful work on the development of protein kinase reporters. Congrats all! www.nature.com/articles/s41...

Grateful to be part of such a fantastic consortium! Huge thanks to our amazing coordinator Christina and to Silke for organizing an inspiring annual meeting in Jena. Latest new: we’ve got a new rising star on the team! #cilia

'Reproductive-associated changes are also known to occur at the organ level, in particular, an increase in intestinal size during pregnancy and lactation has been observed in several mammals such as mice, rats, sheep, and pigs' thenode.biologists.com/re-growing-a...

@sven-m-lange.bsky.social @alanbrownhms.bsky.social epic preprint dropped last night 🔥🔥🔥 #cilia #ift #ubiquitin #compartmentalization #signaling #GPCRs #AnticipationBuilding #SlowRead 🧪 www.biorxiv.org/content/10.1...

Dear cilia researchers, join us in the heart of the beautiful Vosges mountains to share your latest findings! This year, partnership with @for5547.bsky.social and keynote lectures by @micromotility.bsky.social and @mick-lab.bsky.social Registration is now open www.cfc2025.conferences-pasteur.org

Mark your calendars & repost! Join us for the 2026 FASEB Lipid Droplets Conference! July 26-30, 2026 in beautiful Scottsdale, Arizona. Best of all: The FASEB Lipid Droplet meeting is co-locating with the FASEB Phospholipid meeting. Two wonderful lipid communities brought together!

Fantastic lineup again. Can't wait!

More than 2 decades ago the PINK1 protein was found to be linked to Parkinson's disease, but its structure and how it was activated was not known. Until @science.org today. A triumph for cryo-EM and structural biology, introducing new targets for drug intervention. www.science.org/doi/10.1126/...

A critical role for the ER Membrane Complex (EMC) in lipid droplet homeostasis https://www.biorxiv.org/content/10.1101/2025.03.10.642408v1

Our first post on Bluesky! 1/ We are excited to share our latest work, showing that heterooligomerisation drives structural plasticity of Prx1-type peroxiredoxins. www.biorxiv.org/content/10.1... Another fantastic collaboration with the Marcel Deponte lab and Joris Messens lab!

Happy faces and a lot of sunshine at the start of our Spring School on #cilia dynamics! @jayccblab.bsky.social @nathaliejuya.bsky.social @mick-lab.bsky.social @wachtenlab.bsky.social Looking forward to three days of interactions with early career researchers from our cilia network partners!

The EU foreign policy chief has declared that “the free world needs a new leader”, as European leaders threw their support behind Ukraine’s president, Volodymyr Zelenskyy. www.theguardian.com/world/2025/f...