Peter MacPherson

Peter MacPherson

@petermacp.bsky.social

Professor of Global Public Health | Head of Public Health l University of Glasgow | Infections | #Tuberculosis | #HIV | #epidemiology | #episky | #IDSky | #TBsky 🧪🛟

5.4K followers1.5K following277 posts

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We found that #TB epidemics are becoming increasingly urbanised. Important implications for supporting effective public health interventions to end tuberculosis epidemics. 🧪 #MedSky @uofgshw.bsky.social @kchorton.bsky.social @nswartwood.bsky.social journals.plos.org/plosmedicine...

PLOS Medicine@plosmedicine.org

In this systematic review & meta-analysis, Mortazavi & colleagues (@petermacp.bsky.social) investigate urban vs rural differences in #TB prevalence between 2000 and 2024 in 26 low- and middle-income countries, finding that TB epidemics have become increasingly urbanized 🧪 #MedSky plos.io/3O79BqY

Peter MacPherson reposted

#TB is often portrayed as a disease of working age adults, but our new preprint shows prevalence of untreated disease is highest among older adults, who also face the greatest gaps in detection and reporting. www.medrxiv.org/content/10.6...

Peter MacPherson@petermacp.bsky.social

We have a new preprint out: In metaanalysis of 82 #TB surveys (30 countries, 4.6M people), we investigated how prevalence changes with age Untreated TB increases substantially with age, with poorer case detection in older adults. www.medrxiv.org/content/10.6... @uofgshw.bsky.social 🦠🧪🛟

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As TB epidemics concentrate in vulnerable populations and area, we think this is an important new way to measure recent transmission, and target and measure intervention effects. We have now expanded this approach to Lusaka 🇿🇲 and Cape Town 🇿🇦 through a @wellcometrust.bsky.social discovery award.

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We then constructed mathematical models using these data to investigate the impact of: 1. Passive case finding 2. Untargeted community screening 3. Local ARTI-guided screening Health outcomes (life expectancy, DALYs) and costs were investigated using microsimulation.

Compared to PCF, untargeted ACF improved life expectancy by ~3.3 years for people with #TB ARTI-targeted ACF covering 50% of the population identified 80% of people with TB and achieved a lower cost per DALY averted

Firstly, we recruited 1545 children 1-4y using clinic convenience & random household sampling in Blantyre 🇲🇼 6.6% had MTB immunoreactivity, giving an annual risk of TB infection of 2.7%. Risk was highest in the poorest neighbourhoods. There was substantial variation between local neighbourhoods.

Local ARTI was not correlated with case notification rates, indicating barriers to diagnosis. Overall, Mtb immunoreactivity surveillance is a new approach that can help model local TB transmission, identify high-risk areas for intervention, and find TB-exposed children who may benefit from TPT.

Peter MacPherson reposted

Peter MacPherson reposted

See details of 2 #PhD posts based at CVR & 12 other projects based in Finland, Denmark, Netherlandsx Spain & England through the DETECTIVE MSCA Doctoral Network 🦠🕵️‍♂️ 👇

Interested in using genomics, big data and AI to tackle future pandemic threats? The @cvrinfo.bsky.social is recruiting two PhD students through the DETECTIVE Doctoral Network 🦠🕵️‍♂️ shorturl.at/iLrfP

Peter MacPherson reposted

It brings a smile to my face every time I see a paper using ggplot2 😀

Jack Stanley@jack-stan.bsky.social

Published yesterday: 🩺 Data from 12 studies on ~16,000 people diagnosed w/ TB in Zimbabwe 📈 Age at TB diagnosis in Zimbabwe increased by half a year with each passing calendar year 2000-2024 🥼 We need to think of older adults more when considering surveillance, diagnosis and management of TB

Peter MacPherson reposted

Published yesterday: 🩺 Data from 12 studies on ~16,000 people diagnosed w/ TB in Zimbabwe 📈 Age at TB diagnosis in Zimbabwe increased by half a year with each passing calendar year 2000-2024 🥼 We need to think of older adults more when considering surveillance, diagnosis and management of TB

thelancet.comTemporal changes in age at diagnosis with tuberculosis in high-HIV prevalence settings: a pooled multi-cohort analysis from ZimbabweAge at TB diagnosis in Zimbabwe increased between 2000 and 2024. TB programmes must adapt case-finding, clinical services and management for older adults considering multimorbidity, polypharmacy and f...

Peter MacPherson reposted

Four clinical academic jobs @lshtm.bsky.social for people in UK training - Closing this week on Friday

Michael Marks@drmichaelmarks.bsky.social

Academic clinical jobs @lshtm.bsky.social for people in UK clinical training Clinical Lecturers 1) Infectious Diseases (ST3-6) tinyurl.com/4vbjwrkr 2) Paediatrics (ST4-7) tinyurl.com/2hajhbs3 3) Public Health (ST3-5) tinyurl.com/yzd5cmxa Clinical Fellow in Primary Care (ST1) tinyurl.com/mpsmk7zk

Peter MacPherson reposted

Got research, a QI project, case report or education innovation to share? The Med+ 2026 Abstract Competition is now open. A great opportunity for resident doctors to present their work at the RCP's largest specialty conference. Deadline: 30 August. Good luck to everyone submitting!

Royal College of Physicians@rcphysicians.bsky.social

The Med+ 2026 abstract competition is open, giving resident doctors the chance to: 🔹 Receive feedback from leading clinicians 🔹 Win prizes, including £500 Submit now: https://www5.shocklogic.com/scripts/jmevent/Abstract.asp?Client_Id=%27RCP%27&Project_Id=%27MPLUS26%27&System_Id=1

Peter MacPherson reposted

This is excellent work once again. Well done Rachel and the rest of the team.

Peter MacPherson@petermacp.bsky.social

New: Risk & cause of death among people living with #HIV admitted to hospital Overall mortality remains unacceptably high (16%) & probably hasn’t changed since 2000 AIDS-related conditions (72%) esp. #TB (27%) main cause of death dx.doi.org/10.1002/jia2... @uofgshw.bsky.social #IDSky #TBSky 🧪🛟

Peter MacPherson reposted

It's been 10 years since we published our first review of sex differences in #TB prevalence. In this update, we found men remain twice as likely as women to have TB, and disparities have likely widened over time. journals.plos.org/plosmedicine...

Peter MacPherson@petermacp.bsky.social

We updated our review of sex diff. in #TB prevalence In 102 surveys (4.7M participants) men were 2x as likely to have TB than women Evidence consistent with sex differences widening over time 🧪🛟 journals.plos.org/plosmedicine... @nswartwood.bsky.social @kchorton.bsky.social @uofgshw.bsky.social

Peter MacPherson reposted

⏳ One week until applications close | Apply by 23:30 BST, Wed 20 May 2026. 2️⃣ senior academic leader roles to work with Malawi Liverpool Wellcome Research Programme (MLW) Data Science & Computational Modelling Unit + Civic Health Innovation Labs (CHIL) @liverpooluni.bsky.social.

Dr Edward Hill@edmhill.bsky.social

2️⃣ Senior Academic Leader roles available at MLW & @livunichil.bsky.social. #IDsky #EpiSky 🧪 🔗 Professor in Global Health Data Science: my.corehr.com/pls/ulivrecr... 🔗 Senior Lecturer in Mathematical Modelling of Global Health: my.corehr.com/pls/ulivrecr... 🗓️ Apply by 23:30 BST, Wed 20 May 2026.

Fantastic video from @lightontb.bsky.social PhD student Dr Mphatso Phiri, summarising the research he has been leading in Malawi 🇲🇼 to reduce men’s risk of #TB, and benefit men, women and children.

The LIGHT Consortium @lightontb.bsky.social

Why are men more affected by TB in Malawi? Higher exposure starts in adolescence-linked to smoking, alcohol use & high-risk environments. Good news:mobile, community TB testing is reaching more men & connecting them to care. Tackling TB in men protects whole communities: youtu.be/wMP4f05lgHM?...

Peter MacPherson reposted

Why are men more affected by TB in Malawi? Higher exposure starts in adolescence-linked to smoking, alcohol use & high-risk environments. Good news:mobile, community TB testing is reaching more men & connecting them to care. Tackling TB in men protects whole communities: youtu.be/wMP4f05lgHM?...

youtu.beMphatso Phiri - Tackling TB in Young Men and the Effectiveness of Community Outreach in MalawiYouTube video by LIGHT Consortium

Peter MacPherson reposted

Very pleased to be awarded an NIHR Global Health Research Professorship! Will work with partners in Malawi to investigate new approaches to using AI to support #TB diagnosis. @nihr.bsky.social @uofgnews.bsky.social @uofgshw.bsky.social @uofgmvls.bsky.social

@petermacp.bsky.social has received an @nihr.bsky.social Global Health Research Professorship. He will work with partners in Malawi to investigate a new approach to artificial intelligence testing for tuberculosis #TB @uofgnews.bsky.social @uofgmvls.bsky.social www.gla.ac.uk/schools/heal...

Peter MacPherson reposted

In our latest paper in @plosmedicine.org, we explore trade-offs in diagnostic algorithm, coverage, and duration of community screening for #TB, highlighting the importance of symptom-agnostic approaches and the need for strategies to sustain impact when screening ends. plos.io/4tuD2SM

PLOS Medicine@plosmedicine.org

In this mathematical modelling study, Katherine Horton & co assess #TB community screening approaches & their estimated effects on TB incidence & mortality, concluding that methods that capture both infectious & non-infectious TB are needed to achieve sustained case reductions🧪 plos.io/4tuD2SM

Peter MacPherson reposted