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Congratulations to Dr Jeanne Salje on securing new funding to advance research into Lyme disease. The award will support work to better understand the disease and improve diagnosis and treatment. 🔗 www.bio.cam.ac.uk/news/new-fun... @campathology.bsky.social @thecimr.bsky.social

We present the most advanced implementation of a synthetic CO2 fixation cycle in a living cell: rMasp in E. coli. 2/3 of the cycle works already together including fastest carboxylase known on earth, CCR! Nice advance designed and driven by Vittorio Rainaldi authors.elsevier.com/sd/article/S...

We have a medium-term PDRA position open in the York Bioenergetics Lab. The post will continue our fundamental work on mycobacterial bioenergetics and how bioenergetics is affected by some of the game-changing antibiotics being developed against TB. Please repost!

Intrigued how #biomolecularcondensates evolve? Want to work with a condensate system that has a global impact? We’re recruiting a 4-year PDRA to explore the evolution of CO2-fixing pyrenoids: www.jobs.ac.uk/job/DTE394/r... Please repost. #pyrenoids #photosynthesis

Congrats Naiya, @loltrogge.bsky.social and @savagecatsonly.bsky.social! It was an incredible journey to witness and such a cool result. So cool to see the details of a system that couples bioenergy to bicarbonate formation from CO2 in a one-way manner.

🧬 Looking for a PhD in the biosciences? Applications are open for the Cambridge Biosciences DTP, offering fully funded PhD opportunities across a range of research areas. 📅 Deadline: 8 December 2026 🔗 bbsrcdtp.lifesci.cam.ac.uk/how-apply #PhD #Biosciences

This is such a great piece of work about an amazing evolutionary story, every part of this is incredible. Congrats @rudycadenabioevo.bsky.social @evanowack.bsky.social Among other surprises, oxygen scavenging instead of photorespiration is not something I was expecting!

Multistate Enzyme Design Enables Efficient and Stereoselective Multistep Catalysis https://www.biorxiv.org/content/10.64898/2026.09.11.750617v1

So far, fewer than 10 of the hundreds of known human milk oligosaccharides (HMOs) have been synthesized on a commercial scale and added to infant formulas. Plant biologist Patrick Shih of the University of California, Berkeley, is determined to change that. #chemsky 🧪

The real life Muller diagram! @contaminatedsci.bsky.social

Saturn rolls a nat 10! It's a damn weird planet. badastronomy.beehiiv.com/p/saturn-has... 🧪 🔭

We are introducing our new Research Theme Leads! Meet Florian Merkle, a new lead in Molecules and Cells, who is aiming to uncover the mechanistic basis of neurological diseases. Learn more about our #ResearchThemes: bio.cam.ac.uk #BiologicalSciences @phar.cam.ac.uk @florianmerkle.bsky.social

Applications are invited to our programme supporting early career researchers to establish their own independent research groups. Please circulate and further details of how to apply by 25 September are here: www.bioc.cam.ac.uk/research/ind... #Biochemistry #EarlyCareer #Postdocs #Science

Delighted and very proud to see our study (and Anna-Maria's first first-author paper) recently out in PNAS: www.pnas.org/doi/10.1073/... @cambiochem.bsky.social @cruk-ci.bsky.social 1/5

getting close to recreating Jane Richardson's style 😎

Congrats @mackinderlab.bsky.social !!! 🎺🥁

We are happy to announce the nine outstanding researchers from across the country who have been awarded our prestigious Faraday Discovery Fellowships, which support outstanding mid-career research leaders in the UK. royalsociety.org/news/2026/08...

New design for a DIY mini bioreactor from David Jordan in Cambridge - with accurate temperature control, gas composition monitoring, illumination, and pumps for feed and waste - ready for reactor networked arrays. Full details at: (notes.livingphysics.org/build_posts/...)

Machine learning-assisted directed evolution of plant Rubisco www.biorxiv.org/content/10.6...

A microbial growth-coupled platform for in vivo interrogation of Rubisco oxygenase activity www.biorxiv.org/content/10.6...

Join our HFSP team on this amazing project! This will be an experimental postdoc position based in Amsterdam. There will be a more bioinformatic/evolutionary postdoc position based in Cambridge coming up soon. #socialfluids

There are three different size systems (mini, midi, super) to cope with different scales, up to about a kilogram of fresh weight of liverwort per tray for the super size. Can take plants through the entire life cycle - great for plant spore production.

Form I and II Rubiscos Exhibit Temperature Dependent Carbon Kinetic Isotope Effects https://www.biorxiv.org/content/10.64898/2026.06.29.735352v1

Congratulations to Iva Tchasovnikarova who has been awarded the Lister Prize from @thelisterinstitute.bsky.social to expand her work on fundamental epigenetic pathways. Read more about Iva's research group and the Lister Prize: www.bioc.cam.ac.uk/news/iva-tch... #ListerPrize2026 #GurdonInstitute

Chloroplast genome editing of Rubisco boosts photosynthesis and plant growth @utokyo-yamori.bsky.social ! www.nature.com/articles/s41...

Wow! Incredible work especially working in nitrogen fixing bacteria!

Congratulations to @claudiabonfio.bsky.social on her Harrison-Meldola Early Career Prize from @rsc.org for developing biophysical and supramolecular approaches to understand the origins and evolution of primitive cells. Read more about the prize and her lab: www.bioc.cam.ac.uk/news/claudia...

A bifunctional coiled-coil protein generates the membrane-within-condensate architecture of the CO2-fixing pyrenoid @mjonikas.bsky.social lab www.biorxiv.org/content/10.6...

Excited to release #OpenSplice - the impact of >500,000 mutations on the alternative splicing of 600 human exons www.biorxiv.org/content/10.6... Led by @gioia-quarantani.bsky.social + funded by @opentargets.org ‬ @sangerinstitute.bsky.social @crg.eu #cshlsymp26 #RNA2026 @rnasociety.bsky.social

Partitioning of Rubisco activase into the pyrenoidal Rubisco condensate is mediated by a functional protein-protein interaction "https://doi.org/10.1038/s41467-026-70724-5" www.nature.com/articles/s41...

7/8 The full mechanistic model 🏛️: every step gated, every checkpoint structural. A complete blueprint for engineering better gene insertion tools. 🛠️

1/23 New preprint! Been thinking about the origin of cellular life. Specifically, how protocells (or *any* compartments) just aren't enough to support the evolution of increasingly complex cells. You gotta de-Darwinize the parts! The ribosome/genome do this. www.biorxiv.org/content/10.6...

🥳 @savagecatsonly.bsky.social

With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...

A de novo CO2 Reductase Featuring a Cysteine-Ligated Cobalt Porphyrin Cofactor https://www.biorxiv.org/content/10.64898/2026.05.07.723500v1

in vivo mutagenesis technique development continues to heat up, congrats to Max, @erika-alden.bsky.social and the whole team!

Structural Insights into the Coupling Mechanism of Vectorial CO2 Uptake by DAB1 https://www.biorxiv.org/content/10.64898/2026.05.01.722082v1

Hornwort pyrenoids: a terrestrial exception with engineering lessons. @tarobison.bsky.social @fernway.bsky.social @laura-gunn.bsky.social @jcarlosvillarreal.bsky.social academic.oup.com/plphys/advan...

This #EarthDay we're featuring Rockefeller's @flamholz.bsky.social, who studies how microbes contribute to #climatechange and how they could offer solutions to this problem via their metabolisms.

We are recruiting a postdoc interested in using machine learning and AI to understand and control post-transcriptional gene regulation. Please apply and join us at @cambiochem.bsky.social ⏳ Closing date: 16 May 2026 🔗 www.jobs.cam.ac.uk/job/55254 Learn more about us: www.sblab.uk

bbc.com/audio/brand/... Now free for all archaea lovers to hear!

New paper where we report that Npc2 - a shuttle-like lipid transfer protein - in yeast directly transports sphingolipids to the = vacuole membrane during formation of microautophagy-linked ordered domains #lipidtime www.sciencedirect.com/science/arti...

Out recently in @natbiotech.nature.com — first authors @ddingding.bsky.social and @evangroover.bsky.social premier a cell-based method for understanding how #photosynthesis genes can be turned "up" or "down". Read here: ow.ly/KHWg50YyWbR

📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.

Excited to see the major chapter of my PhD in print! We present a massively-parallel approach for screening CRISPR edits in plants to speed up agricultural test cycles + benchmark genomic LMs. Thanks to my fantastic co-authors and advisors. Link below!

Can CRISPR edits enable precise tuning of plant gene expression? We think: yes. In our newest manuscript, we measured the effects of >30,000 CRISPR-like promoter mutations in sorghum protoplasts.

We have been cooking up this story for a while and we are excited to finally be able to share! Read on if you're interested in whole plant regeneration WITHOUT the application of hormones!

Out today in Nature Biotechnology — a team of IGI scientists including Brian Staskwicz, Kris Nyogi, Dave Savage (Savage Lab), Peggy Lemaux, & first author Evan Groover premier a cell-based method for understanding how #photosynthesis genes can be turned "up" or "down" https://ow.ly/KHWg50YyWbR

Expansion microscopy of a loricate choanoflagellate, generated by Mylan Ansel in our lab 🤩 (yes, the lorica expands. No, we don't understand how either)

Archaea hit prime time: www.bbc.co.uk/programmes/m...