Ruth Montgomery

Exogenous nitric oxide as an anti-infective agent. New review from Carl F. Nathan @weillcornell.bsky.social: rupress.org/jem/article/... #InnateImmunity #inflammation #InfectiousDisease #HostDefense

Our "Single-cell multi-omics in IPF & COPD: from atlas to impact" is out! We provide a brief guide to analytic approaches, an overview of how the technologies impact our understanding of the 2 diseases, limitations, future directions. publications.ersnet.org/content/erj/...

Fresh off the press... www.jove.com/t/70816/spat...

To share how the immune system is connected to health, Dr. Edward Doherty answered patient questions on the immune system’s role in autoimmune disease at the Autoimmune Community Summit. Thank you, Dr. Doherty, for all you do as an Immunology Explained Ambassador!

Celebrating #HHMIInvestigator Dana Pe’er (@mskcancercenter.bsky.social) on her election as a member of the National Academy of Medicine! Recognized for pioneering foundational computational frameworks to infer cellular information from single-cell & spatial data, & more: bit.ly/4ysMYyk

Had a grant rejected once that said I needed a machine learning expert on the team despite 25 yrs ML experience & hundreds of ML publications

Out today in @jcb.org! Work from the Mogessie, Fachinetti & Redemann labs reveals how CENP-A/B/C cooperate to maintain kinetochore function in oocytes and how declining centromere strength predisposes aging eggs to aneuploidy. doi.org/10.1083/jcb.... @health.pew.org @valleefoundation.bsky.social

Congratulations to our wonderful colleague Dr. Erica Herzog @yalemed.bsky.social, we look forward to continuing to work with you and all of yoru section!

Amazing new dimensions of multiplex tissue analysis--congratulations Lingyan Shi and my Yale colleagues! @rongfan8.bsky.social @yalemed.bsky.social

2 genetically identical mice. Same infection, same bacterial load, but only 1 lives. Why? #HHMIInvestigator Janelle Ayres spent decades finding out, & her answer — survival can come through cooperating w/pathogens, not just killing them — could reshape how we treat infectious disease: bit.ly/4qsuWJW

The most pressing questions in immunology — why do people respond differently to infection, vaccination or therapy? Why do some develop chronic inflammatory disease while others remain resilient? See high-dimensional public data resources. @hipcproject.bsky.social @yalemed.bsky.social rdcu.be/fAwms

Hi @msmacrophage.bsky.social wishing you a great march and great discoveries to all

Chemist & X-ray crystallographer Rosalind Franklin's meticulous research was instrumental in uncovering DNA's molecular structure. Most famous for her role in the DNA double helix discovery, her work also revolutionized our understanding of viruses & coal. She was born #OTD in 1920. #WomenInSTEM 🧵

Another red alert for American science | Science www.science.org/doi/10.1126/...

m.yale.edu/dh3y

Can eating less help us age better? Research has long shown that cutting calories can improve lifespan in some species, but it’s not always practical or healthy for people. Now, a study from immunobiologist Vishwa Deep Dixit is exploring how we might get those same benefits without the risks.

Excited to announce our new study (w/ @maxkrummel.bsky.social) published today @nature.com: Macrophages “hold our living identities” by taking tiny bites from living cells and presenting this information to CD8 T cells. www.nature.com/articles/s41... #immunology #cellbiology @immunox.bsky.social

Thank you to the incredible panel of researchers who presented at the Immune Development in Early Life Hot Topic Symposium at @pasmeeting.bsky.social #PAS2026 L to R: Dr. Xiaobin Wang, Dr. Ofer Levy, Dr. Oluwabunmi Olaloye, Dr. Octavio Ramilo, Dr. Paolo Palma. #vaccines #IDEAL #EarlyLifeImmunity

We focus on human immunology to understand the effects of #aging. Great science being shared at @hipcproject.bsky.social annual meeting by @adamtanguay.bsky.social from @yalemed.bsky.social

After the HIPC Symposium, meet some of our researchers and speakers at our Immunology Superbooth in the exhibition center! At booths #736 #738 @aai.org

@skleinstein.bsky.social presenting on @immportdb.bsky.social and @hipcproject.bsky.social work at #AAI2026 💡

We have age-associated macrophages in visceral fat making C3a and increasing inflammation. C'mon macrophages, we need your help here. Wonderful new paper from Dixit lab @yalemed.bsky.social #SenNet www.nature.com/articles/s43...

#AAI2026: Besides our #HIPC Guest Symposium, we will have two presentations from members of our #ImmuneSpace team ( @skleinstein.bsky.social & Jian Xing) on Saturday, April 18th! Hope to see you there at @aai.org 💬💡🙂

Members of our Data Management and Analysis team had a great time at NextGenOmics, Spatial & Data US! Joann Diray Arce, PhD gave a talk on ImmuneVISTA and MultiOMICs in #vaccine research #NGOUS2026 #OGPREMED #vaccines

Congratulations to my wonderful Yale colleagues!

Working together to advance understanding of human immunology. Well said Holden! @hipcproject.bsky.social

FACT OF THE DAY. 26 March 1953. In a huge medical breakthrough, US medical researcher Dr Jonas Salk announced that he had created the first polio vaccine. Polio cases fell from 58,000 per year in 1952 to 6,000 by 1958. Salk’s vaccine was replaced by a new one developed by Albert Sabin in 1962.

🎉 Congrats to #AGE2026 Early Career Scholar Awardee Piper Wilburn- #IndianaUniversitySchoolOfMedicine. Recognized by the #AmericanAgingAssociation, her research studies how the bone marrow niche shapes stem cell function and transplant outcomes in aging. #Geroscience #AgingResearch

Good discussion of the disappearing NIH Notices of Funding Opportunity (NOFOs). elizabethginexi.substack.com/p/the-nofo-g...

www.tandfonline.com/doi/full/10....

I love phagocytosis- the most ancient form of immunity (estimated at 1 billion yrs old!). Lucky to geek out with all the other macrophage and neutrophil geeks at beautiful Keble college, Oxford.

New clues to understand #HealthyAging from @yalemed.bsky.social studying longevity in nature. #SenNet www.science.org/doi/epdf/10....

Sharing on behalf of Dr. Florian Krammer for those interested - his podcast is great! Episode 0 of my new podcast viroLOGICAL is online. This first episode is a little longer and gives a general overview of viruses and viral diseases. Find it on Apple, Spotify, and Podigee: virological.podigee.io

Learning lots about #lung autoimmunity as a contributor to severe #asthma from Dr Manali Mukherjee from #TheFirestone. Great reminder that blood is not always the right place to sample for autoimmunity -sputum can be a much more informative marker.

Both chambers of Congress have now passed the FY26 minibus with NIH provisions. The President will sign. (1) $48.7 billion for NIH (2) Full IDC recovery (3) No more multi-year funding (4) No NIH reorganization, maintaining the current IC structure.

m.yale.edu/dfrz

Thank you to Bob McDonald for hosting me on @CBCRadioCanada to discuss our work @yaleschoolofmed.bsky.social on what leads to variation in common cold virus infections and how we tackled this using nasal organoids. Listen here: www.cbc.ca/listen/live-...

Glad to join today in teaching #CyTOF for Yale's Computational Proteomics course directed by Dr. Maria Rodriguez Martinez. Multidimensional single cell immune profiling for #HIPC takes a team including Dr. Adam Tanguay and Dr. Ashish Shelar.

My most recent manuscript is available from @pnas.org . We describe a population of inflammatory cytokine MIF responsive T cells and their importance in Rheumatoid Arthritis pathogenesis.

Solo markers were interesting but combining gene SNPs and plasma metabolite data showed predictions for severe #COVID. That's why we study the whole #SystemsImmunology #BigScience #Teamwork

Dr. Leila Denmark co-developed the pertussis (whooping cough) vaccine. World's oldest practicing pediatrician until she retired at age 103 (after 73 yrs). At the time of her death at age 114 & 60 days, she was the 5th-oldest validated living person in the world & 3rd-oldest in the US. #WomenInSTEM

I am excited to share our new paper @JExpMed led by our one and only #Alejandra_Aroca

Representative Betty McCollum (D-MN, 4th) met with AAI Councilors Gwendalyn Randolph, Steve Jameson, and CPA Chair Lauren Ehrlich! They had a great conversation about how crucial robust funding is for NIH. Thank you for the support! #AAIadvocacy

AAI Councilors Donna Farber, Avery August, and Laurie Harrington had a wonderful meeting with staff from Rep. Josh Riley’s (D-NY, 19th) office, discussing the importance of NIH funding and science-based policy. #AAIadvocacy

The NIH grant cuts in 2025 www.nytimes.com/interactive/...

Super excited for the upcoming #cellbio2025 @ascbiology.bsky.social @embo.org meeting in Philadelphia! Check out the Special President's session on "The Rising Tide of Science Denial" on Saturday at 1pm!

We are proud to feature 2025 RCCN Pilot Awardees Lauren Ferrante and Kathryn Callahan in this Pilot Awardee Spotlight! Learn more about their Inter-NIA Center pilot project here: bit.ly/4izqwNF #Frailty #AgingResearch

Honored to be recognized as one of 25 Best Leaders by @usnews.com including 5 in the Health category. I look forward to meeting some extraordinary colleagues at an upcoming event in Wash DC www.usnews.com/news/leaders...

The Trump admin has been targeting whistleblowers, from the #FEMA36 to the countless other patriotic public servants and scientists across NIH, CDC, NASA, and more who spoke out about the danger posed by the chaos in our federal agencies. This is an concerted, autocratic effort to silence dissent.

New research from Dixit lab @yalemed.bsky.social showing nerve-associated macrophages (NAMs) decline in aging which impairs the breakdown of fat and increases inflammaging. Dixit addresses the biology of aging and intercommunication between nerves and macrophages. www.nature.com/articles/s43...