Sergio Menchero

Sergio Menchero

@sermenchero.bsky.social

Postdoc at @crick.ac.uk | HFSP fellow | DevBio, epigenetics, marsupial, evo-devo | Previous Manzanares lab | #embryo2017 | (he/him)

437 followers597 following86 posts

Pinned

Sergio Menchero reposted

📢 We are excited to announce our latest work on oocyte meiotic checkpoint signalling @crick.ac.uk Led by George Sioutas, the work allowed us to delineate the early steps of the checkpoint signalling program of pre- and postnatal oocytes 🐭🧬https://www.biorxiv.org/content/10.64898/2026.10.13.758765v2

biorxiv.orgStage-specific checkpoint signalling by ATM, ATR and DNA-PK safeguards oocyte genome integrityIn somatic cells, DNA double-strand breaks (DSBs) are potentially catastrophic lesions that activate phosphatidylinositol 3-kinase-related kinase (PIKK) signalling to promote DNA repair or eliminate d...

Sergio Menchero reposted

👩‍🔬BioScaPe PhD position in the lab! 🧫 Investigate & compare stress susceptibility in progenitors and neurons across species, in collaboration with Axol Bioscience. 🔗 More info and how to apply > www.babraham.ac.uk/work-and-stu... 📢 Please share with anyone who might be interested!

Sergio Menchero reposted

Sergio Menchero reposted

Sergio Menchero reposted

🚨 #Postdoc position open. Want to understand non-canonical #epigenetic regulation of mammalian transcription? Come work @uoe-igc.bsky.social in Edinburgh! We’re looking for a motivated & collaborative colleague with a strong track record. 📅 14 October 2026 📢 Please share Apply here 👇

elxw.fa.em3.oraclecloud.comPost-Doctoral Research AssociateAn exciting postdoctoral position is available to research the role of epigenetic marks in gene regulation.

I couldn't recommend this enough!

Teresa Rayon@trayon.bsky.social

‼️ Postdoc position open. We study how protein metabolism controls time. If you’re excited by this question, we’d love to hear from you! We’re looking for a motivated & collaborative researcher with a strong track record. 📅 30 September 2026 📢 Please share Apply here 👇👇

Sergio Menchero reposted

Sergio Menchero reposted

Few days left to apply! Please like and share to spread the word!

Niakan Lab@niakanlab.bsky.social

We have a postdoc position available in the lab and would like to spread the word. Please apply if you are interested! www.cam.ac.uk/jobs/researc...

Sergio Menchero reposted

Hello World ! Reminder about our open postdoc position 🧪🧬 Reviewing applications until October - get in touch to know more about what's hot in the lab these days ! Application details in the post below 👇👇 #EvoEpi #MolaroLab #watwat #ERC

Antoine Molaro@antoinemolaro.bsky.social

Hello World ! We have another postdoc position open in the lab! Are you a freshly minted Ph.D. with a passion for chromatin and evolution ? Come join our ERC project #EvoEpi ! Inclusive environment + cool people + great science = success details 👉 tinyurl.com/3r6zk54n Repost are always appreciated

Increasing and decreasing proteasomal activity affects the pace of neural differentiation. Beautiful work linking protein production and degradation to developmental tempo ⌛

Teresa Rayon@trayon.bsky.social

Our work on the role of the proteasome in developmental tempo is out!!!! 🐭⌛️👤⏳ Six years after identifying an association between protein stability and developmental tempo, we now demonstrate a causal link between protein turnover and developmental tempo through proteasomal degradation

Beautiful work on evolutionary novelties! Top Evo-Devo 👀

Isabel Almudi@isabelalmudi.bsky.social

What happens when evolution adds an extra pair of eyes? Male mayflies evolve an extra pair of dorsal compound eyes, the Turbanate eyes, thought to help males detect females during mating swarms. we have investigate how this remarkable evolutionary novelty develops. www.biorxiv.org/content/10.6...

Sergio Menchero reposted

⭐Postdoc position available⭐ How do symbionts evolve new beneficial functions? Join the Henry Lab to investigate how horizontal gene transfer drives host–microbe symbioses. 🦠 Apply below Enquiries: l.henry@qmul.ac.uk Please share! #Postdoc #EvolutionaryBiology #Symbiosis henry-lab.co.uk

qmul-jobs.tal.netPostdoctoral Research Associate in Evolution of Host–Microbe Symbioses - QMUL JobsID: 10612. Title: Postdoctoral Research Associate in Evolution of Host–Microbe Symbioses. Application Deadline:

Sergio Menchero reposted

Hello World ! We have another postdoc position open in the lab! Are you a freshly minted Ph.D. with a passion for chromatin and evolution ? Come join our ERC project #EvoEpi ! Inclusive environment + cool people + great science = success details 👉 tinyurl.com/3r6zk54n Repost are always appreciated

Sergio Menchero reposted

The 2nd part of my postdoc is now out as a preprint! A challenging but fulfilling team effort to perform genome editing in opossums. We found that the lncRNA RSX is essential to initiate X-inactivation in marsupials 🦘 A long-standing question since the discovery that Xist is absent in marsupials 👇

Turner Lab@lab-turner.bsky.social

New preprint 📢 Thrilled to share our long-awaited work on the role of RSX in marsupial X-inactivation. This was a huge team effort over the years, led by @aureliencourtois.bsky.social @sermenchero.bsky.social Sugako Ogushi and Waz Varsally, that allowed us to set up genome editing in opossum embryos

The power of cross-species comparisons 🎏 A quantitative definition of heterochrony comparing the transcriptome of (fast) zebrafish and (slow) medaka embryos. And no, not everything in medaka is slow!

Mike Dorrity@mwdorr.bsky.social

First pre-print from the lab, a collaborative effort led by Jess Bourn @bournsupremacy.bsky.social, a fantastic PhD in my group. We resolve a key problem in development + evolution: how do we quantify heterochrony and link temporal variation to phenotype? www.biorxiv.org/content/10.6...

Sergio Menchero reposted

Sergio Menchero reposted

We’re looking for a technician to join our lab in Dresden - help manage the lab and work with us on a cool 'stem cell zoo' comparison projects! 🐁🚶‍♀️🦏🐒 Apply by May 21! tud.link/wbqrwm

Physics of Life Dresden@poldresden.bsky.social

🚨 #JobAlert: Lab Technician. Please share with your colleagues! 👩‍🔬The Ebisuya lab @ebisuyamiki.bsky.social is looking for an experienced technician in molecular & cell biology to join their interdisciplinary team. Apply now! Learn more here 👉 tud.link/wbqrwm 🗓️Application deadline: May 21.

Sergio Menchero reposted

Join us for the 2026 YEN conference on the 15th of June at the Francis Crick Institute! Only two weeks left for the abstract deadline!

Marta Perera@martaperera.bsky.social

Don't forget to register for the Young Embryologists Network (YEN) Conference 2026! Francis Crick Institute, London June 15th, 2026 Abstract Deadline: May 13th, 2026 Lots of opportunities for talks from abstracts! Link: forms.gle/fxtmNHjEziVTFprN6 #DevelopmentalBiology #ReproductiveBiology

Sergio Menchero reposted

Last day to submit an abstract! This is a meeting aimed at all career stages, but especially geared on early career scientists (PhD/postdoc), don't feel you need to have a perfectly polished story to present!

Alex de Mendoza@alexdemendoza.bsky.social

May 5th: if you are around London, please join the London #EvoDevo symposium at QMUL / Charterhouse campus, as usual we will have selected talks and post-event 🍻. A warm up for #EED2026 in Glasgow. Registration £0, more info here: londonevodevo.co.uk

This is so cool!

Alex Neaverson@alexneaverson.bsky.social

I illustrated my way through the @bsdb.bsky.social Spring Meeting a couple weeks ago - here's my illustrated summary of the conference! I sketched (almost) all the speakers and glimpses of the science that made it such a great few days.

Sergio Menchero reposted

The time has come for another round of QBMM - we have a fantastic lineup of speakers in genomics, systems biology, and modeling cell dynamics. Check it out! Co-orgs @elowitzlab.bsky.social @tinekelenstra.bsky.social @trayon.bsky.social @savitski-lab.bsky.social and I look forward to seeing you

EMBL Events@events.embl.org

Join #EMBOOmics which aims to showcase new technologies and formulate questions to move the systems biology field forward 👉 s.embl.org/omx26-01-bl 📥 Abstract deadline 11 September

Sergio Menchero reposted

Sergio Menchero reposted

The Cooper lab is hiring a postdoc with a strong background in mouse genetics and molecular biology to advance.our gene drive work. Must be extremely organized, engineering-minded, and outcomes-oriented. Spread the word and have interested candidates email me directly.

Honoured and grateful to receive the 2026 BSDB Dennis Summerbell Award. This was the cherry on the cake of a fantastic meeting. Thank you @bsdb.bsky.social and the whole DevBio community for being so inspiring

🏆 We’re delighted to announce the winner of the 2026 BSDB Dennis Summerbell Award! This year’s award goes to Sergio Menchero @sermenchero.bsky.social, recognised for exceptional contributions to developmental biology and for carrying forward the curiosity and rigour that Dennis championed.

Sergio Menchero reposted

🚨 Job Alert - Please share! 🙏 Interested in 3D gene regulation in development & evolution? 🤓🧬 💥 Our lab at @cabd-upo-csic.bsky.social is expanding! We’re recruiting: ✅ PhD students ✅ Postdocs 💻🧪 Experimental or computational backgrounds welcome 👇 Details below

Sergio Menchero reposted

Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here: rdcu.be/e5EgU #EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜

rdcu.beThe molecular evolution of vertebrate organsNature Ecology & Evolution - This Review discusses recent advances in the molecular evolution of vertebrate organs, including rates of evolution of organs and cell types, molecular mechanisms...

Sergio Menchero reposted

To kickstart this new Bluesky account: We're hiring! The Bertolin Lab @dundee.ac.uk is looking for a postdoc to work on DNA-end homeostasis & genome stability, funded by Wellcome Trust Award. Exciting science, fantastic environment, founding role in the lab. Details in the flyer — get in touch! 👇

Sergio Menchero reposted

PDRA position still open in my lab for anyone who wants to solve some outstanding questions in limb development. We have a variety of models and approaches (everything from stem cells to chicks and catsharks). Please share!

Matt Towers@matt-towers.bsky.social

A BBSRC-funded PDRA position is available in my lab investigating vertebrate limb development! Please contact me for more details. www.jobs.ac.uk/job/DQH553/r....