Tom Yates

NEW PAPER in @lancetmicrobe.bsky.social! We show that recent household transmission makes a limited contribution to overall TB burden Should motivate greater focus on social protection and interrupting transmission in indoor congregate settings Thanks to coauthors - particularly Martha Chipinduro

Good! The first in a string of critical elections over the next few days

Is it possible, for each study, to estimate uncertainty around where the inflection point is, then to take these point estimates with their associated confidence intervals, and test for heterogeneity, as you would in a meta analysis? #statsky

Rodeo2 results!

Anyone know whether headline results of the Rodeo2 trial are available? Oral amox for streptococcal endocarditis I hear rumours it was presented at ISCVID 2026, but can't find an abstract online? Thanks #IDSky

Statistical friends, imagine you had data on the association betwen two continuous variables across a number of different settings Slope levels off at some point What would the best approach to testing whether the inflection point differed between settings? #statsky

Enjoyed this. Also, science is usually a sport played by teams, so making awards to individuals, duos or trios is problematic

This is really terrible news. Helen was one of the best. Helen Branswell, whose reporting on infectious diseases and public health drew acclaim, dies at 69 www.statnews.com/2026/10/13/h... via @statnews.com

Statistical friends, imagine you had data on the association betwen two continuous variables across a number of different settings Slope levels off at some point What would the best approach to testing whether the inflection point differed between settings? #statsky

In other news, Lance Armstrong had some big wins in the Tour de France #LIVMCI

The other Post Office scandal: how organised crime launders money on the high street

Trump's latest extraordinary betrayal of Ukraine

As well as being daft, for the technical reasons Dan Neidle lays out, the policy tells us an awful lot about the priorities of the Tory Party

This recording of Curtis Flowers singing 'I won't complain' is extraordinary

Are there good data on bone penetration for MDR TB drugs, incl the new ones? Particularly interested in penetration into bones with poor blood supply. Presumably quinolones and LZD get in okay. What about the other drugs? #TBsky

Rare good news

Further evidence that being rich is one of the best things you can do for your health

Already very wealthy people agreeing to participate in lucrative sportswashing projects for vile dictatorships says an awful lot about about their character

Well, there we have it. No ending rough sleeping in the UK then that's for sure.

“Aiding and abetting foodborne illness may be lettuce’s biggest offense. But it doesn’t have much else going for it, either, and there’s a reasonably strong case that we would be better off without it.”

I don't understand this. We need a right sided winger and better full back and defensive midfield options. Why not make offers for Camavinga and Mbaye?

I find the argument made here problematic. Either it is ethical to randomise to a placebo or it isn't. I'd do response adaptive randomisation.

I wish media outlets would describe Nathan Cofnas as a racist rather than a "self-defined race realist" which doesn't mean anything to most people. His writing meets any definition of racism however narrowly and cautiously drawn.

Academia is full of over promoted white people, many of whom have exagerated their achievements. Unbelievably sad.

Demystify clinical trial design & enhance your research toolkit!📊✨ Join our statistical seminars supported by @advance-id.bsky.social & @who.int Explore clinical trial theory & real-life examples with global experts. Master the numbers in the mission against disease here: ad-id.co/stats

Excited to now able to say funded @nihr.bsky.social for Streptococcal Adaptive Platform Trial (STRAP!) Evaluating 1) Optimal backbone anitibiotics 2) Benefit adjunctive anti-toxin antibiotics 3) Benefit IVIG Collab with Australia (hope also NZ & Canada) building off SNAP. Aim open in UK in 2027

We all know the long banned imprisonment for public protection sentence is inhumane. Another review will just kick the can down the road yet again. All Andy Burnham need to do is introduce a bill to re-sentence prisoners still serving IPPs. By me. www.theguardian.com/commentisfre...

Can we get a UX engineer involved in the clinical trial governance process please

Are there packages to run IVhet meta-analyses in R or Python? I have implemented in Stata but my Gen Z colleague is not impressed by that ... #StatSky

Walthamstow please share - the big pre loved school uniform sale will be from Wednesday 12th August at the Salvation Army on Forest Road. Every item - including blazers - 50p and most local schools covered. Save money and save carbon by reusing well kept uniform! #loveWalthamstow

At the moment, people on Health & Care Worker Visa have no recourse to public funds. Why deny social security if they e.g. injure themselves at work? Treating carers with respect should include looking after them if they fall on hard times. Current rules deeply exploitative @stellacreasy.bsky.social

Has anyone got this paper in pdf? #TBSky

Cloning, censoring and weighting is often used to estimate impact of treatment duration on outcomes Presumably, it can also be used to estimate the impact of delays in starting treatment? #episky

And here's AFP picture taken by one of the photographers in the PA picture, Justin Tallis

Raising the personal allowance is very poorly targeted Loads of the money will go to people who are already comfortably off, and households where one or more workers earn less than the current threshold get little or nothing Much better to raise universal credit, I would have thought?

New Comment Reconsidering the rVSVΔG-ZEBOV-GP vaccine during the 2026 Bundibugyo virus outbreak www.thelancet.com/journals/lan...

I consistently voice concerns about the idea drilling rosebank would be good for either the climate or the cost of living crisis - in the coming days as this debate returns I will continue to be a voice for prioritising the transition to clean energy for the sake of our pockets and our planet.

Academic clinical jobs @lshtm.bsky.social for people in UK clinical training Clinical Lecturers 1) Infectious Diseases (ST3-6) tinyurl.com/4vbjwrkr 2) Paediatrics (ST4-7) tinyurl.com/2hajhbs3 3) Public Health (ST3-5) tinyurl.com/yzd5cmxa Clinical Fellow in Primary Care (ST1) tinyurl.com/mpsmk7zk

I've just had an analysis accepted for publication that I began working on 14 years ago - some drinks will be had tonight!

[boldly] I just don't think the British government needs to have Shabana Mahmood in it, I think we managed fine without her and we can just keep going without her, it's fine, Andy Burnham doesn't need to find a space for her in cabinet, there are other MPs

Very glad to see this moving at speed I volunteered in a previous ChAdOx1 Ph1 Ebola vaccine trial, and was well looked after

I had a lovely time attending the EEPE genetic epidemiology course - learned loads. Thanks to @uclpophealthsci.bsky.social for funding my attendance - also green travel - via a Catalyst Award

Why is this not standard? I would also love the option to opt out of copy editing So many wasted hours changing tuberculosis back to Mycobacterium tuberculosis, and vice versa ...

Measurement folks, is there a literature on validation by proxy? E.g. you have a dataset in which you can validate measure A against gold standard, and another dataset containing measure A and measure B. Can you infer measures of validity for B? Some sort of network validation ... #episky #statsky

Surely it is now time for drug policy reform Less violence, fewer people rotting in prison, better care for people who use drugs, big savings for tax payers Politicians need to be brave @andyburnham.bsky.social @stellacreasy.bsky.social