Adrian Wanner

The Transmitter @thetransmitter.bsky.social just published a piece on this: www.thetransmitter.org/connectome/b...

two new preprints from Wangchu Xiang (@darbly.bsky.social, Ginty labs) about connectomic reconstruction from electron microscopy of somatosensory afferents and projection neurons in the dorsal horn of the mouse spinal cord www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6...

Precise structural and functional organization of the olfactory bulb neuropil early in development, revealed by volume EM, dense reconstruction and 2P calcium imaging in zebrafish. Great work by Ruth and others in collaboration with @michalwj.bsky.social www.biorxiv.org/content/10.6...

A few words about what I’ve been up to at Flourish. Reach out if this resonates with you and you’d like to talk! fewerbetterfaster.substack.com/p/the-parts-...

Applications are now open for the San Juan Winter School 2027 on Connectomics and Brain Simulation! Join us to learn how to analyze and simulate connectomes. sjcabs.com

Very happy our work on a weird new nanoscale morphological feature is out in @science.org. A massive effort involving different high resolution microscopy techniques, multiple institutes, & years of work to convince ourselves DENDRITIC NARROWINGS EXIST #neuroskyence 🧪 doi.org/10.1126/scia...

Just out in Nat Neurosci: disentangling of neural odor manifolds in "olfactory cortex" of adult zebrafish after learning. Great work by Bo, Nesibe et al and wonderful collaboration with @sueyeonchung.bsky.social that fundamentally changed my view of olfactory cortex. www.nature.com/articles/s41...

We are hiring! Start at a #MaxPlanckInstitute with your own independent Max Planck Research Group. This position is equivalent to a W2 Professorship at a German university, or Associate Professor internationally. 🔗Apply until October 14th! www.mpg.de/career/max-p... #ScienceCareer #MPRG #TenureTrack

Ultrastructural reconstruction of hundreds of neurons by volume EM revealed cell types and a precise glomerular organization in the zebrafish olfactory bulb. A heroic effort by Nila! Special thanks to Nila @michalwj.bsky.social and the whole team! www.biorxiv.org/content/10.6...

Imaging of activity in the telencephalon of adult zebrafish moving through a virtual reality revealed amazingly precise, structured internal representations of spatial environments. And they get better over time! Great work by Kim! Thanks also to Sriram and Jan. www.biorxiv.org/content/10.6...

New preprint by Tommaso: olfactory cortex (of zebrafish) represents not only odor information but also temporal context, and these multimodal representations are sharpened after learning. And check out Tommaso's new method for 2P imaging in awake adult zebrafish! www.biorxiv.org/content/10.6...

Fish with electrical senses have unique brain cells specifically to process that information. The real trick they pull is separating the electricity they emit from the ones they sense. 🧪 Link: https://www.nature.com/articles/s41586-026-10690-6​

We're thrilled with the publication of the Male CNS Connectome! www.cell.com/cell/fulltex... Also check out this (growing) collection of companion papers: www.cell.com/consortium/m...

I finally got around to posting the HHMI Connectomics Berlin conference snapshots: bryanwjones.com/2026/07/hhmi... Some of ya'll are in here.

Happy to share the CA3 dataset is published. First large-scale dense connectomics from hippocampus. First connectomic dataset imaged in @princetonneuro.bsky.social. A harbinger of many larger datasets to come (for both). doi.org/10.1038/s415... #hippocampus But my personal favorite is (1/2)

Excited to share our work now in Nature Methods! We wrote this manuscript to help others better analyze and interpret calcium imaging data. As a central aspect, we show why nonlinear behavior of calcium indicators matters in practice. Very happy about this work!

New preprint! www.biorxiv.org/content/10.6... Nearly a decade after starting the project, the first major results from our comparative connectomics work is online! Comparing the head direction circuits of the central complex in bees, ants and flies, recapitulating >300million years of evolution.

Sharing a big update: I started a group at the MPINAT in Göttingen! We will develop AI for analyzing how proteins interact in the cellular environment based on cutting edge imaging. This appointment is in parallel to the university, where I will retain my current group.

Here are my slides for #fens2026 “A versatile and affordable array tomography workflow” https://jekelylab.codeberg.page/FENS_Array_Tomography_Barcelona_July2026.html#/title-slide for the 'Expanding Horizons: Array Tomography in Neuroscience for All' […] [Original post on biologists.social]

If you’re in or around Baden today, drop by... because Pint of Science Switzerland is back in town for a third time this year! 🧠 "Cracking the Brain's Code" 📆 Today: 19 May, 2026 📍 Kulturhaus Royal, Bahnhofstrasse 39 ⏰ Doors open: 6 PM pintofscience.ch #pintofscience

Can generative AI accelerate neuroscience? Excited to share MoGen at ICLR 2026!🧠 We use point cloud flow matching to generate high-fidelity 3D neuron fragments, capturing intricate details like dendritic spines.

This work was a collaborative effort between our lab and clinical experts at UPK Basel. The parallel approach of using mouse circuit and human patient data is likely the most promising approach we have to understanding the mechanism of psychiatric treatments. Full paper: doi.org/10.64898/202...

New preprint with @sevberg.bsky.social! We map Hopfield-like binary networks onto spiking networks with dendrites … and it works! Same memory capacity, bigger basins of attraction, plus selective recall through dendritic gating, and more. How? Dendrites! See below.

Great opportunity to shape the future of X-ray connectomics (and much more 😉): @psi.ch is looking for a new head of the Center for Photon Science www.psi.ch/en/hr/job-op...

#paper: Drying tissue samples enhances contrast in X-ray phase contrast imaging while largely preserving ultrastructure. 🧠🔬 doi.org/10.1107/S160... @safekhan.bsky.social @andreas-t-schaefer.bsky.social @crick.ac.uk @embl.org @imperialcollegeldn.bsky.social @esrf.fr @uclnpp.bsky.social

“We’re hoping doors will open for researchers to ask questions about how connections are made in the brain in mice and maybe, one day, humans.” - @andreas-t-schaefer.bsky.social Read about the new NIH-funded program to map brain circuitry using X-rays: www.crick.ac.uk/news/2026-03...

Exciting new results from our neighbors in the @mace-lab.bsky.social! Using functional ultrasound imaging, they look at brain-wide activity patterns in response to arousing events, showing propagation from subcortical regions to the cortex, and find a surprisingly weak modulation by noradrenaline!

How do fish localize sound without interaural cues? @johve.bsky.social et al. found a behavioral algorithm for directional hearing that predicts behavior from a pressure/motion phase comparison and accounts for how this relationship varies with distance. www.cell.com/current-biol...

Job alert! Join the Making Lab at the @crick.ac.uk. As a senior engineer in system design, programming, and hardware–software integration, you'll develop systems that make unique experiments possible. More about the role and apply here: crick.wd3.myworkdayjobs.com/External/job...

From @bdpedigo.bsky.social: a super efficient, highly reliable, and very generalizable method for mesh structure classification, applied here to spine detection across basically every synapse onto a cell in the MICRoNS dataset.

The Wiley Foundation is pleased to announce the winners of the 24th annual Wiley Prize in Biomedical Sciences, which recognizes contributions that open new fields of research or advance concepts in a particular biomedical discipline. Learn more: https://ow.ly/ZaiM50YhCF6

In @eLife: Neural connectome of the ctenophore statocyst https://doi.org/10.7554/eLife.108420 Version of record of our ctenophore nerve-net connectome paper.

What it's like to be a connectome

The winner of the 2026 Pradel Research Award is H. Sebastian Seung of @princetonneuro.bsky.social! He is being honored for for transformative advances in computational neuroscience. Learn more about his discoveries: www.nasonline.org/award/pradel... #NASaward #neuroscience

What's the relation between voltage and calcium in dendrites? Xiang Wu studied this in CA2 hippocampal pyramidal cells in behaving mice. www.biorxiv.org/content/10.6...

🔬🔦Our latest ‘Imaging spotlight’, by @carlesbosch.bsky.social, Ana Diaz, @adrianawanner.bsky.social & @andreas-t-schaefer.bsky.social, highlights the non-destructive X-ray tomography pipeline that the authors developed to map mouse brain ultrastructure & considers future applications & developments.

If you are interested in electron microscopy, registration is still open for the "Electron Microscopy Hands-On Course: sample preparation and imaging of marine environmental samples" at Stazione Zoologica in Naples. WIth great teachers from Naples […] [Original post on biologists.social]

Our dispatch: https://www.sciencedirect.com/science/article/pii/S0960982225014691 on the recent Hydra volume EM paper by Zhang, Rafa Yuste and colleagues: #connectomics, without synapses https://www.sciencedirect.com/science/article/pii/S0960982225013090 #neuroscience

How do neural circuits generate the walking rhythm? Using connectome simulations, @sarahpugly.bsky.social found a minimal central pattern generator (CPG) that produces oscillations in leg motor neurons. Same circuit motif for each 🪰 leg. w @bingbrunton.bsky.social www.biorxiv.org/content/10.1...

Last night Adam Kampff, the glue, the light, the catalyst, the builder, the smile, left us. He and his work transformed the lives of many labs, scientists, students. He inspired and was generous to his last transformation, working tirelessly to set up a foundation to continue the work.Thank you!

Our Method of the Year 2025 is...drumroll please...EM-based connectomics!! Our Editorial introduces our choice and highlights six Comments and other related content in this special issue. Please join us in celebrating EM-based connectomics! 🎉🧠🔬 www.nature.com/articles/s41...

Connectomics is Method of the Year 2025!! @natmethods.nature.com just released the news nature.com/articles/s41... In my perspective piece, I afford some predictions into the future and compare how we are doing vs. genomics www.nature.com/articles/s41...

Connectomics is method of the year 2025: www.nature.com/articles/s41...

An optimized X-ray nanotomography method offers an attractive alternative to volume EM for connectomics. @crick.ac.uk @psich.bsky.social psich.bsky.social @adrianawanner.bsky.social @andreas-t-schaefer.bsky.social @ucl.ac.uk @uclnpp.bsky.social www.nature.com/articles/s41...

Our new paper showcasing molecular connectomics with pan-expansion microscopy is out in @natbiotech.nature.com! www.nature.com/articles/s41... This wonderful collaboration with @bewersdorflab.bsky.social was led by Ons M'Saad (now founder/CEO of Panluminate) and @allisonphysics.bsky.social. (1/5)