Pinned
Now I can say: last week we received Notice of Award from NSF on a Midscale Research Infrastructure Design proposal for a National Connectomics and Ultrastructure Volume Observatory (NCUVO) www.uvm.edu/uvmnews/news...
Davi Bock
@dddavi.bsky.social
Rural neuroscientist. Connectomics. Protists. caveat emptor: https://bsky.app/profile/dddavi.bsky.social/post/3k5bnogiq5r2j
2.3K followers509 following365 posts
Pinned
Now I can say: last week we received Notice of Award from NSF on a Midscale Research Infrastructure Design proposal for a National Connectomics and Ultrastructure Volume Observatory (NCUVO) www.uvm.edu/uvmnews/news...
Davi Bock reposted
The future of biology is not just about collecting more data, but also about uncovering new principles and deriving new understanding. Theory and expts go hand in hand! See www.asimov.press/p/theory-bio... Excited that Theory & Concepts is back for the 3rd edition: come join us at EMBL next July!!
Are you curious about theoretical and quantitative approaches to understanding living systems? Then you should not miss out on #EESTCBio! 🧬 Submit your abstract by 13 Apr to explore how biology can be understood, not just measured: s.embl.org/ees27-06-bl
Davi Bock reposted
We are hiring an AI@HHMI Program Manager to help run HHMI's $500M AI initiative: projects, budgets, staffing, recruiting, events, outreach. Advanced degree, program management experience, fluent with AI tools and effective without them 😉. Work with me! hhmi.wd1.myworkdayjobs.com/en-US/Extern...
Now I can say: last week we received Notice of Award from NSF on a Midscale Research Infrastructure Design proposal for a National Connectomics and Ultrastructure Volume Observatory (NCUVO) www.uvm.edu/uvmnews/news...
The Transmitter @thetransmitter.bsky.social just published a piece on this: www.thetransmitter.org/connectome/b...
Davi Bock reposted
two new preprints from Wangchu Xiang (@darbly.bsky.social, Ginty labs) about connectomic reconstruction from electron microscopy of somatosensory afferents and projection neurons in the dorsal horn of the mouse spinal cord www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6...
Davi Bock reposted
Davi Bock reposted
Davi Bock reposted
If you are interested in serial sectioning for electron microscopy, we have now uploaded a revised version of our paper Shahidi et al: "Volume Electron Microscopy: Tips & Tricks on Micromanipulator-Assisted Serial Sectioning for Array Tomography" […] [Original post on biologists.social]
Very nice to see this extension + (most importantly) functional assay of our initial observation of non-random overconvergence of food-responsive PNs onto downstream aB and a'B' KCs (@zhihaozheng.bsky.social et al. Curr Biol 2022). Connectomics leading to testable hypotheses: as it should be!😀
Our paper on odour categorization in the Drosophila mushroom body is now out in Cell Reports! 🎉 We found that αβ and α′β′ Kenyon cells—but not γ KCs—distinguish food-related from non-food odours at the population level. Very happy to see this work published! 🪰🧠 doi.org/10.1016/j.ce...
here's a link to @zhihaozheng.bsky.social et al.'s paper if anyone is curious: www.cell.com/current-biol...
Davi Bock reposted
Our paper on odour categorization in the Drosophila mushroom body is now out in Cell Reports! 🎉 We found that αβ and α′β′ Kenyon cells—but not γ KCs—distinguish food-related from non-food odours at the population level. Very happy to see this work published! 🪰🧠 doi.org/10.1016/j.ce...
Claude has a privacy setting for whether or not your sessions can be used to train their models. I'd like to know what the setting was in this case.
Four days ago, a scientist was surprised by the news that Anthropic discovered new virus genes for making DNA. He says he’s been studying them for years—and feeding his data to Anthropic’s AI as part of his own research. Coincidence? Here’s my story. nyti.ms/3VSWayc
Davi Bock reposted
new #preprint: t.co/eE1qqGSflK Ben Hartl explains: In 1917, D'Arcy Thompson drew Cartesian grids around different anatomical shapes & showed that deforming the grid could change one species' shape into that of another. We find that "reusable regulatory handles control phenotypic variation" in NCAs
Davi Bock reposted
Protists deserve the spotlight and so do scientists! This was such an honor but mostly, this project reminded me why I have the best job and friends/colleagues in the world! 🔬
Many scientists feel grim right now. Here's a different story - about discovery, friendship, grimness, yes, but how science finds a way! @couchmicroscopy.bsky.social @andrewilloughb.bsky.social In an $80 Motel Room, a Discovery to Shed Light on the Origins of Life www.nytimes.com/2026/09/26/s...
Davi Bock reposted
Georgios Skiniotis and I are announce a unique St. Jude faculty search: a joint effort between the CoE for Structural Cell Biology an intellectual community advancing structural imaging & the Division of Neuronal Cell Biology. CryoET/vEM + neuron cell biology = 🚀 talent.stjude.org/careers/JobD...
this is interesting in its own right and because Flourish raised $500m to develop new AI architectures based at least in part on neuroanatomy data they plan to acquire. (see flourishlabs.ai/flourish_wir...)
A few words about what I’ve been up to at Flourish. Reach out if this resonates with you and you’d like to talk! fewerbetterfaster.substack.com/p/the-parts-...
Davi Bock reposted
We are hoping that word of this search goes far and that we draw a wide and diverse pool of applicants. Please take a look and share if you're inclined. 5 departments involved! • Organismic & Evol Bio • Mol & Cell Bio • Stem Cells & Regen Bio • Earth & Planetary Sci • Human Evolutionary Bio
Hello friends, the Harvard Life Science departments have banded together to hire a new colleague working at the intersection of Life Sciences and AI. Could be primarily an experimentalist, or could be primarily a compute/theorist. academicpositions.harvard.edu/postings/16773
Davi Bock reposted
Replying to @dudinlab.bsky.social
For two weeks, our entire lab is dropping everything to focus on one mission: deploying @embl.org's Advanced Mobile Laboratory to cultivate microbial eukaryotes from Alpine ecosystems. Our dream? Isolating new #Ichthyosporeans never cultured before. Let's see what we find. 🔬🏔️
Davi Bock reposted
Davi Bock reposted
Applications are now open for the San Juan Winter School 2027 on Connectomics and Brain Simulation! Join us to learn how to analyze and simulate connectomes. sjcabs.com
Davi Bock reposted
We're hiring! Join us as a postdoc to study how the brain is optimised for sensory coding and memory Please spread the word! Apply at jobsite.sheffield.ac.uk/job/Research... Deadline: 5 October 2026 Learn more at: www.aclinlab.org
nice job by my former mentee @zhihaozheng.bsky.social :)
Our September issue is now live! www.nature.com/neuro/volume...
Davi Bock reposted
Replying to @nicolecrust.bsky.social
That contextual signals are broadly available does not mean that signals everywhere are used, or causally involved in behavior, at every moment. They aren’t. A bit like a radio broadcast, information may be widely available while circuits selectively “tune in” when needed. So where still matter.
I’m happy to see all this movement but still want to see how the various optical methods work out at scale.
@adammarblestone.bsky.social says mapping a whole mouse brain once looked like about a $10B, 15-year project. He argues that's now down to $100–200M and a few years, with a focused effort — and lays out why. Full conversation on the @juanbenet.bsky.social Podcast >>> youtu.be/X0B_GWTuEFo
Davi Bock reposted
Last week to apply for these posts. This a great time to join this project — every week we’re finding out new and exciting things about the organisation of the mosquito brain — with super collaborators @darbly.bsky.social and @megyounger.bsky.social. Pls share!
Mosquito Aedes aegypti brain connectome project is super exciting: jobs available Elizabeth Marin & @jefferis.bsky.social recruiting Research Assistant and Postdoctoral Research Associate Deadline: 3 September 2026 Brilliant colleagues & bosses - highly recommend flyconnecto.me/2026/08/01/t...
Davi Bock reposted
Thanks to @bwjones.bsky.social for the polite education... I had no idea that glutaraldehyde-linked small molecules can indeed be detected in this way, by antibodies raised against the same small molecules cross-linked to BSA. bwjoneslab.com/wp-content/u...
Perhaps also explains the sale of “antibodies” for physically implausible targets (like L-/D-glutamate, GABA, dopamine) that can’t provide any epitope, because they are simple small molecules. Link to just one of many examples www.immusmol.com/landing/glut...
Davi Bock reposted
Davi Bock reposted
Mosquito Aedes aegypti brain connectome project is super exciting: jobs available Elizabeth Marin & @jefferis.bsky.social recruiting Research Assistant and Postdoctoral Research Associate Deadline: 3 September 2026 Brilliant colleagues & bosses - highly recommend flyconnecto.me/2026/08/01/t...
Davi Bock reposted
Do you want to be part of the RCP (www.raynorcerebellumproject.org) effort to usher in the next generation of closed loop neuromodulation? Work with a one of a kind human dataset? Collaborate with top groups all over the world? Apply. cdn.prod.website-files.com/679cf22d773c...
Davi Bock reposted
Davi Bock reposted
Davi Bock reposted
🚨 Now out in @aaas.org Science Advances 🚨: aDISCO: a protocol for clearing & antibody-staining human formalin-fixed paraffin-embedded (FFPE) tissue by Anna Maria Reuss! 🧠🔬#lightsheet #Microscopy @mesospim.bsky.social @ptrrupprecht.bsky.social www.science.org/doi/10.1126/...
Davi Bock reposted
My newsletter turns five years old this month. It's time to take stock of where the climate is, and where the fight is. billmckibben.substack.com/p/take-five-...
Davi Bock reposted
Happy to share the CA3 dataset is published. First large-scale dense connectomics from hippocampus. First connectomic dataset imaged in @princetonneuro.bsky.social. A harbinger of many larger datasets to come (for both). doi.org/10.1038/s415... #hippocampus But my personal favorite is (1/2)
Davi Bock reposted
#FluorescenceFriday Our lab studies microglia: microscopic 🔬 immune cells in the retina 👁️ We label them with Green Fluorescence and catalog of some impressive types! @flaumeye.bsky.social @urneuroscience.bsky.social @uofrbme.bsky.social @cvsuor.bsky.social @urochestersmd.bsky.social bit.ly/4kMNErh
Davi Bock reposted
Come join the @socialfluids.bsky.social lab in Cambridge to study the evolution of Socially Transferred Materials! Fun new HFSP project btwn UK, NL and Costa Rica! Deadline September 7th #Postdoc #JobAlert #Evolution #Bioinformatics #STM #socialfluids www.cam.ac.uk/jobs/researc... leboeuflab.com
Davi Bock reposted
New preprint! www.biorxiv.org/content/10.6... Nearly a decade after starting the project, the first major results from our comparative connectomics work is online! Comparing the head direction circuits of the central complex in bees, ants and flies, recapitulating >300million years of evolution.
Davi Bock reposted
Biology is once again full of surprises most if us couldn’t dream up if we tried.
Avocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor www.pnas.org/doi/10.1073/...
Davi Bock reposted
How does the brain know where the body has been touched? In our new eLife paper, we map how touch-sensitive bristles on the fruit fly head connect to circuits that guide precisely aimed grooming, revealing how brain maps turn touch into action. (elifesciences.org/articles/108...)
Davi Bock reposted
Do #tintinnids dream of electric sheep? 🤯 Here is a single cell capable of building a lorica and living inside it for protection... it also swims, feeds, hunts Can even detect and habituate to mechanical cues! #celllearning #protistsonsky #cilia Read more in our preprint doi.org/10.64898/202...
Davi Bock reposted
This profile of the artist on the Challenger expedition and his contributions to protistology was a very nice Saturday morning read. Though with some irksome bits...
On the artist of the iconic sketch of Globigerina: J.J.W. Article in free access for 50 days at authors.elsevier.com/a/1nPdH56A9x... #protistsonsky