Seth Coffelt

I will hire a Postdoc to study the genomic determinants of tumor heterogeneity Please, get in touch if interested, or help me spread the voice @scilifelab.se @kawresearch.bsky.social @liu.se liu.se/en/research/...

www.cell.com/trends/immun... @coffeltlab.bsky.social

A good moment for people and organisations to abandon their presence on Twitter/X and stop supporting Elon Musk's hate platform was four years ago. The second best moment was two years ago. And then last year. A few months ago: late but still OK. Definitely now. There's no excuse left to stay.

Jasmine Clark will become the first Black woman with a science Ph.D. to serve in the U.S. House of Representatives. https://scim.ag/4dDZe6P

Online now: Interleukin-17-Producing γδ T Cells Originate from SOX13+ Progenitors that Are Independent of γδTCR Signaling

If you are interested in PARP inhibitors and history, this might be of interest to you. www.nature.com/articles/s41.... An attempt to cover the work of thousands and their immense contributions to the development of a targeted approach to treating cancers.

Meanwhile on VE Day, marking the unconditional surrender of right-wing extremism and fascism in Europe.

ICYMI: New online! γδ T cells in colorectal and liver cancer

Doing the periodic cleaning of used plasmid miniprep columns and realized in honor of Earth Day it may be worth reminding you molecular biologists: Plasmid miniprep columns can be cleaned and reused essentially indefinitely! Just add 1 M HCl, soak overnight and wash 3x w/ water. Save $ and plastic

📣We've summarized all there is to know about mouse #gdTcells in cancer and how they relate to humans @immunowolf.bsky.social #AbhiramMallu #NataliePhinney check it out here: authors.elsevier.com/sd/article/S...

We spend under $50 billion a year on NIH…

Check out this lineup 🎉 Join us the last week of June for 100% cancer immunology

Portraits of some of the researchers that The Regime has run off. We are losing so many excellent researchers.

Vγ1 γδ T cells steer airway macrophages toward a profibrotic response in an autochthonous lung cancer mouse model #gdTcells @coffeltlab.bsky.social

*Recruiting new group leaders* The @lmcb-ucl.bsky.social at University College London are looking for outstanding candidates to sponsor for career development fellowships. Fellows would then be assessed for tenured positions at the end of the fellowship term.

Check out this lineup 🎉 Join us the last week of June for 100% cancer immunology

Detection of metastatic burden is a task for CODA, which maps organs in 3D and at single-cell resolution. More here: www.biorxiv.org/content/10.6...

Join us for our March #GDTcellclub webinar talks with Drs. Judith Wienke (Utrecht) and Monika Wolkers (Sanguine BSF) on March 19 at 12pm NY time. Zoom ID: 958 9051 7066/ passcode 369081 nyulangone.zoom.us/j/9589051706...

Helpful update into UKRI and research council funding changes from Zoe Kleinman @zsk.bsky.social But please more focus on 2 things... 1) Immediate effects (eg funding decisions expected in March) 2) Likely disproportionate effects on early career scientists www.bbc.co.uk/news/article...

BREAKING: Over 680 members of the National Academy of Sciences, Medicine, and Engineering have endorsed articles of impeachment against RFK Jr. (1/2 🧵)

More than 7,800 research grants terminated or frozen. Some 25,000 scientists and personnel gone from agencies. Proposed budget cuts of 35% — amounting to US$32 billion. These are just a few of the ways Donald Trump has downsized and disrupted US science go.nature.com/4sTPWdp

Climate change news The three seasons in the UK are now Easter, summer and Christmas.

📢Are you a talented #ECR looking to start your independent lab in state-of-the-art cancer research facilities? Join the CRUK Scotland Institute & @uofgcancersciences.bsky.social as a Junior Group Leader! 👉Apply here: www.crukscotlandinstitute.ac.uk/careers/grou... 📅Closing date: 10 October 2025

Was "Let's make our universities financially dependent on overseas tuition fees." Then "Let's make it more difficult and less attractive for overseas students to come to the UK." Now "Oops."

Super proud to see our work featured on the cover of @emboreports.org today. Many thanks to @pedromics.bsky.social for this beautiful interpretation and depiction of our story. Read the associated paper here: www.embopress.org/doi/full/10....

check out our new commentary on 2 recently published papers about #gdTcells in breast cancer www.sciencedirect.com/science/arti...

No one has done more damage to public health and trust in science and medicine than Andrew Wakefield. 26 years after his wrong and fraudulent paper people are still spouting his nonsense about an alleged link between vaccines and autism. The study was debunked countless times. There is no link.

MO Gov Mike Kehoe is calling a special session to gerrymander the 5th District which encompasses Kansas City. He is specifically violating Section 2 of the Voting Rights Act, which bans any voting practice that denies or weakens the power of a racial minority to elect its preferred candidates.

www.oncology-central.com/tackling-tnb...

Proud to share an exciting study on the metabolic changes observed in the body before the spread of breast cancer. This seminal work could pave the way for early interventions and more positive outcomes for patients. Congratulations to all involved! www.embopress.org/doi/full/10....

The Junior PI call @ccii-kyoto.bsky.social is open until the end of the month. Join us in Kyoto! 👇 #Immunology #Immunotherapy #Immunosky

ICYMI: In pancreatic cancer even localized disease poses a threat to long-term survival due to early metastasis. @brianpedro.bsky.social & Laura D. Wood @jhu.edu review the most common PDAC precursors and highlight opportunities for pancreatic precancer interception. buff.ly/xQ0ediG

💥 Check out our latest review article just out @cp-trendscancer.bsky.social @cellpress.bsky.social doi.org/10.1016/j.tr... In this paper, we carefully review multiple aspects that tightly link #platelets to #metastasis

When the reviewers' identities are revealed

Schmidt Fellowships for #AI in #cancer research 2025 round is now open. These are pathway to independence fellowships between @icr.ac.uk & @imperialcollegeldn.bsky.social that support fellows to be competitive for faculty jobs at the end of the 2 year funding. www.imperial.ac.uk/jobs/search-...

Huge thanks to these 3 pals who raised £11k for @beatsoncharity.bsky.social www.glasgowlive.co.uk/news/glasgow...

Are you looking for a postdoc? I will be looking for 2-4 people after the summer to join the lab !! Do not hesitate to reach out and disseminate !!

"Our President will start a war with Iran because he has absolutely no ability to negotiate. He's weak and he's ineffective." - Donald Trump, November 2011

Did you know that #GTSRC has a spinoff meeting? If you study #GI #epithelium and are looking for a smaller meeting to network and share ideas, then #GESRC25 is for you! Join organizers Mike Verzi, Matt Ciorba & Katie Garman in Southbridge, MA on Sept 7-11, 2025. #Gastosky #GIsky bit.ly/3FLsSKx

As a child from poor, uneducated parents, I was never thought to succeed. And now here I am, being ranked as one of the top 1% scholars in Medicine. To all kids out there being doubted: Never give up. For all adults: Be the one person who believes in a child. scholargps.com/search.php?q...

“Ending a $5 million research study when it is 80% complete does not save $1 million, it wastes $4 million.” ✊🏼🧬 www.standupforscience.net/bethesda-dec...

📣 Postdoctoral position available!!! Are you interested in translating molecular cell biology into potential cancer therapy? This project will explore the role of EGFR trafficking in chemotherapy resistance in #breastcancer 🔬 Prof Liz Smythe lab 📅 Deadline: 3rd Jule 👇 www.jobs.ac.uk/job/DNJ622/r...

Glasgow Caledonian University scientists, led by Dr Timothy Humpton, have discovered a new scientific pathway to prevent fatty liver disease, caused by Western diet high in fat and sugar, from progressing to deadly liver cancer. 👏 🔗 Read more: www.gcu.ac.uk/aboutgcu/uni...

news.cancerresearchuk.org/2025/06/09/t...

@gounismichalis.bsky.social‬ et al. show that cells that seed early lung #metastasis in #BreastCancer have altered #metabolism. These metabolic alterations lead them to release extracellular vesicles which engender a microenvironment conducive to invasive growth. rupress.org/jcb/article/...

Organoids Are Us 2025 📅 23 - 26 September 📍Glasgow, Scotland Early bird registration deadline: 15 June Organised by @mrcmousenetwork.bsky.social‬ and @cruk-si.bsky.social‬ Find out more:

Exciting #organoids meeting in Glasgow, just after the summer!

Lovely new paper from @leedham-simon.bsky.social dissecting epithelium-microenvironment crosstalk through BMP & wnt signalling in the intestine. Inhibition of BMP antagonist GREM1 may forestall polyp formation in Hereditary Mixed Polyposis Syndrome (HMPS). www.nature.com/articles/s41...

We are looking for a postdoctoral fellow to come work with us: www.cruk.manchester.ac.uk/career/mi-25... Please reach out