The @fillouxlab.bsky.social is growing and having fun. Very pleased to have such a nice @scelse.bsky.social group in Singapore @NTU and working on #T6SS#Biofilm#c-di-GMP#Pseudomonas#antibiotics. So let's refresh the pinned group's photo with this one.
PhD project available in my lab at Newcastle University looking at the elasticity of a unique bacterial outer membrane (found in M. tuberculosis) with some fun biophysical tools to probe its mechanical properties! 🦠🔬
Fall 2027 start. Apply by 24 Nov 2026.
www.findaphd.com/phds/project...
The story of the short-lived (1868-1875), but widely believed, primordial life form of Huxlely & Haeckel - a pictorial biography -
www.openscience.fr/A-pictorial-...#protistsonsky
In 1929, Alexander Fleming published his paper outlining the antibacterial properties of penicillin, and paved the way for a new era of antibiotics.
Read the Nobel Prize laureate's full article online: https://t.co/fPKDufTlbD#OpenAccessWeek
Just finished reading "Microbe Hunters" (1926). What a book!
It brings to life the great discoveries of microbiology - and, even more, the people behind them: Leeuwenhoek, Pasteur, Koch, and others who revealed the invisible world shaping disease, wine, beer, and food
1/5
🦠
Cracking the Archaeal Cell Wall: How a hydrolase overturned a 50-year-old paradigm
The story behind the paper!
"...our nemesis, the 85Da mass, was present in all tested species and was still inexplicable…"
communities.springernature.com/posts/cracki...
A methanogen hydrolase reveals the structure of archaeal peptidoglycan
www.nature.com/articles/s41...
🦠
Shareable link to read the paper: rdcu.be/FJXrUPAdeswa
Congratulations to Prof Alain Filloux, Research Director of SCELSE’s Biofilms & Health cluster, named a ScholarGPS® Highly Ranked Scholar: #1 in Secretory Protein and #16 in Pseudomonas aeruginosa (Lifetime All rankings). He ranks among the top 0.05% of scholars. @fillouxlab.bsky.social
New in JB: Harrison, Chen et al., using CRISPRi and imaging, describe the "order of operation" of divisome assembly in C. difficile, an organism lacking some of the canonical cell division proteins.
journals.asm.org/doi/10.1128/...@asm.org#JBacteriol@microsky.bsky.social
🔬 Working at the intersection of microbiology and biotechnology?🚀
The Biotechnology track at FEMS MICRO 2027 invites researchers exploring these topics.
Submit your abstract by 15 Dec: buff.ly/nmJ2Kso
New in JB: Middleton & Jones propose a dimensional analysis framework as a means to quantify biofilms as well as compare findings across the literature. And they show 3 examples of such an analysis as proof of concept.
journals.asm.org/doi/10.1128/...@asm.org#JBacteriol@microsky.bsky.social
PhD project available in my lab at University of Warwick: "Using super-resolution microscopy to investigate the mechanistic principles of bacterial cell wall remodelling"
September 2027 start date. Apply by 23rd Nov 2026. Informal enquiries by email, with CV.
www.findaphd.com/phds/project...
💥 Post-doc opportunity! 💥 Come join our team (www.thelowlab.org) at Imperial, London, working on the cryo-EM structure and mechanism of bacterial secretion systems. 48 months. Please RT.
For more details and to apply:
www.imperial.ac.uk/jobs/search-...
New in JB: Zhan, Du et al. provide evidence that in the elongasome, MreC alternates between an active and an inactive state and interacts with PBP2 and RodZ, indicating a key regulatory role for RodZ.
journals.asm.org/doi/10.1128/...@asm.org#JBacteriol@microsky.bsky.social
VACANCY - We’re looking for a Postdoctoral Researcher to join the @Barrie Wilkinson Group, in collab with the @Matt Hutchings lab, on a project: Global activation of silent and cryptic biosynthetic pathways in Streptomyces species.
Deadline - 26 October 2026
Contract - 36 months, full-time
Added something to chimerax-trimmings that I have wanted for ages!
Added old Chimera-style model controls, so that one can freeze or activate specific models and freely rotate/translate them with respect to one another.
Implemented as modelmotion in latest version.
github.com/olibclarke/c...
The new target of Dr Rokas Juodeikis's research is to develop ‘next generation probiotics’ that protect against or even reverse age-related decline of the brain and eye and to test these in a clinical trial 🧠
buff.ly/EMEPK27
A major part of my PhD is out in ASM’s mSpectrum! We tracked pathogen interactions in children with CF including 𝘗. 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢, 𝘚. 𝘢𝘶𝘳𝘦𝘶𝘴 and 𝘏. 𝘪𝘯𝘧𝘭𝘶𝘦𝘯𝘻𝘢𝘦.
𝘗. 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 showed reduced antagonism already in early childhood.
journals.asm.org/doi/10.1128/...
🔬 Share your research at FEMS MICRO 2027, whether as a poster display, flash talk, or session talk; there is a place for your work.
Submit by 15 Dec for the opportunity to present in Ljubljana, Slovenia, 5-8 July 2027.
📄 buff.ly/trsmmi5
Beetles secrete jelly to embed & sustain symbionts with impossibly tiny genomes🪲
But what is this jelly made of? And how does it help maintain a partnership that has lasted over 62 million years?
Thrilled to share our latest, out now in @natcomms.nature.com!
www.nature.com/articles/s41...
NEWS - Beetles build with a yellow pigment gene 🪲
More than 80 years ago, scientists discovered that differences in yellow pigmentation were critical to courtship success and failure for fruit flies.
🧵
Gut microbes shape the body’s response to vaccination. Researchers led by Ruth Ley discovered that the human gut microbiome may help determine how strongly the immune system reacts to vaccination, with bacterial flagellins contributing to inflammatory responses:
www.bio.mpg.de/569449/news_...
🆕 Blog! A Quadram Early Career Fellowship has primed Dr Rokas Juodeikis to develop next generation probiotics against age-related conditions, through the @uniofeastanglia.bsky.social Jonathan Knowles Research Fellowship 💊
buff.ly/h2t4Eti
Thinking about submitting an abstract for #FEMSMICRO 2027 but not sure where to start? 🔬
Remember the 4 C's of abstract writing:
✅ Completeness ✅ Conciseness ✅ Clarity ✅ Cohesiveness
A strong abstract explains not only what you did, but why it matters.
Find out more: buff.ly/Nk7hoEa
Fellows from our European Academy of Microbiology (EAM) came together at the 2026 EAM Summit, 7-9 October, to forge interdisciplinary links stretching across the full breadth of microbiology.
FEMS is magnifying microbial impact through the EAM, Europe's expert body of microbiological minds.
Cover image alert 🎨🚨👇🏼 - check out the amazing drawing of Sophia Zimmermann from our group in Nature Microbiology @natmicrobiol.nature.com !
Fun fact: Sophia initially drew it as a present to Dorentina @humollidorentina.bsky.social when we celebrated her recent paper on TnSeq with phages 🥂😊.
We wrote a short “Behind the Paper” post about our HIDEN-SEQ journey together with @aharms485.bsky.social.
Check it out: go.nature.com/4yBHsdy
Special to share it with the @natmicrobiol.nature.com cover, featuring the amazing art of the great scientist and artist Sophia Zimmermann from our lab!
Another step in the #Starship story - they move via a circular intermediate.
Helps explain how these elements horizontally transfer and means that we can modify them into transformation vectors (starmids).
www.biorxiv.org/content/10.6...
Meet the first of our creative postdocs: “I'm Daniela Ramirez, a postdoc studying plant-bacteria interactions and fascinated by microbes living within plants. My research uses bGWAS to uncover how Pseudomonas infects and colonizes Arabidopsis thaliana.”
#PAWGermany#PAW2026#PostdocAppreciationWeek
ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use.
We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition.
github.com/PacesaLab/Bi...
#AMR superbugs are getting tougher, but predatory bacteria like B. bacteriovorus can hunt them down! We show that model bacterium E.coli 🦠 can escape these ‘living antibiotic’ by evolution, mainly through OmpF porin loss. This comes at a cost. Details at: tiny.cc/2qpa101#MicroSky, #Evolution
#InternationalMicroorganismDay is a great time to share a work just published in ISME Journal; a massive collaborative network at Forschungszentrum Jülich and Heinrich Heine University Düsseldorf by @frunzkelab.bsky.social and colleagues
#Community & #siderophoresacademic.oup.com/ismej/advanc...
Giulia Manina gets the @events.embl.org workshop on “The complexity of
mycobacterial infections” underway at the @pasteur.fr.
Looking forward to five days of talks and talking.
Exploiting the bacterial type III secretion system of Pseudomonas aeruginosa to impact genomic recombination in murine lungs
www.sciencedirect.com/science/arti...
🦠 Feeling trusted: The FEMS Council in Stockholm elected me to be the 18th president of the Federation of European Microbiological Societies 🧫
This is quite an incredible position that makes me happy and proud and really looking forward to the tasks ahead.
We are delighted to announce Michael Sauer (@michlwien.bsky.social) as the next FEMS President, alongside three new members of the FEMS Board of Trustees, Ivica Dimkić, Celia Manaia and Martyna Glodowska.
Read more: fems-microbiology.org/fems-elects-...
Spirochetes do it differently!
Evolutionary characterization and structure-guided discovery of the β-barrel assembly machinery in Treponema pallidum subsp. pallidum reveals a putative BamD-like protein
www.sciencedirect.com/science/arti...#MicroSky
At the start of 2026, EMBL lost long-serving colleague and Interim Director General Peer Bork. Join us in commemorating Peer and his legacy at the #EMBLBorkMemorial.
Submit your abstract by 10 November: s.embl.org/pbs27-01-bl