Federico Lopez

Federico Lopez

@flopezos.bsky.social

Evolutionary biology, genomics, bioinformatics, social insects.

861 followers1.1K following47 posts

Federico Lopez reposted

Putin apologists want you to buy that: -An alleged off-the-books 1991 verbal promise outweighs a signed 1994 treaty -Democratic countries formerly occupied by Russia asked to join an anti-Russia alliance for no reason -Ukrainians don't want freedom, an American tricked them into it with cookies

📄 Bumblebees use and repair artificial honeypots 🐝 "[W]e asked whether bumblebees would use artificial 3D-printed honeypots... Bees readily used the complete artificial honeypots and completed the partial honeypots to produce a variety of resulting structures." doi.org/10.1016/j.cu... ⬇

Federico Lopez reposted

🚨 UPD: A woman was killed and at least three others were injured after Russian forces struck the National Academy of Sciences of Ukraine in central Kyiv.

Federico Lopez reposted

This is horrifying. Fourteen people were murdered and 121 injured, including 22 children as russia attacked the largest mall in Kryvyi Rih on Friday afternoon. 29 people are in severe condition.

Federico Lopez reposted

Federico Lopez reposted

Replying to @aphillippy.bsky.social

A major strength of T2T genomes is that they cleanly resolve heterozygous variation, complex repeats, and segmental duplications that are lost with short reads, including nearly 400 medically relevant genes, the MHC, and most of the Y chromosome. What have we been missing? [8/15]

Federico Lopez reposted

For the past 30 years, “whole-genome sequencing” has been a misnomer. Today the T2T Consortium publishes a dozen papers heralding a future of truly complete genomes for humans and nearly any vertebrate 👨‍🔬🐒🐦🐀🦒🐎🫏🐹🐟 (sorry, no salamanders): www.cell.com/consortium/t... 🧵[1/15]

Federico Lopez reposted

Federico Lopez reposted

Federico Lopez reposted

Federico Lopez reposted

Just had a great zoom with a very talented undergraduate student from another country I would love to recruit. I really don't love telling students not to come here, but because our funding and visa situation is so volatile I can't in good conscience recommend a PhD in the US.

Federico Lopez reposted

Federico Lopez reposted

Federico Lopez reposted

Federico Lopez reposted

Our paper is out! 📣 we find that molecular measures of genetic variation do not predict heritable genetic variation across species - important implications for the application of genomic data for conservation! www.pnas.org/doi/10.1073/...

pnas.orgNucleotide diversity is a poor predictor of short-term adaptive potential | PNASThe capacity to adapt is essential for a population to avoid extinction in a changing world and is recognized as a global conservation priority. Ad...

Federico Lopez reposted

Our new genome annotation method relies almost entirely on transcriptome and alignment evidence, and as a result outperforms pretty much all other de novo pipelines. Check out the just-published paper led by Aleksey Zimin: rdcu.be/frSOg

rdcu.beEfficient evidence-based genome annotation with EviAnnNature Methods - EviAnn surpasses existing genome annotation methods by leveraging gene expression and protein sequence homology evidence to achieve higher accuracy and efficiency.

Federico Lopez reposted

Federico Lopez reposted

A new Science study shows that bumble bees can position a ball underneath a fake “flower” to reach a reward, suggesting they can exhibit spontaneous problem-solving and challenging the notion that such advanced cognitive abilities are exclusive to large-brained vertebrates. https://scim.ag/4vs08dC

Federico Lopez reposted

The first single-cell three-dimensional lamprey brain atlas reveals that the vertebrate common ancestor already had a highly regionalized brain, and subsequent neuronal specialization likely drove vertebrate brain diversification. Learn more this week in Science: https://scim.ag/4whLqXp

Federico Lopez reposted

Minibwa is a hybrid of bwa-mem and minimap2 and the successor of bwa-mem for short-read mapping. ~4X/2.5X as fast as bwa-mem/bwa-mem2 for WGS reads at comparable accuracy. Native support of directional bisulfite-seq. Applicable to long reads. Preprint at arxiv.org/abs/2606.15357

Federico Lopez reposted

The heaviest Russian air attack on Kyiv in two weeks saw several people killed and the Pechersk Lavra monastery, a symbol of Ukrainian spiritual and cultural history, catch fire, authorities said.

Federico Lopez reposted

Nineteen russian ballistic missiles, cruise missiles and Shahed drones are raining down on Kyiv right now. This is horrific. The UNESCO-listed Kyiv-Pechersk Lavra has been targeted. A thousand years of Ukrainian history, faith, and culture are once again under attempted destruction.

Federico Lopez reposted