A side project that got out of hand—in the best way 🚀 New paper is out: www.nature.com/articles/s41... We sequenced the first Clusia genomes to understand something subtle but fundamental: 👉 CAM is a drought adaptive mechanism in plants - how do different physiotypes of CAM evolve? A 🧵 👇 1/14
Johannes Herpell
Johannes Herpell
@herpell.bsky.social
Microbes | Plants | Ecology | Climbing | Cycling | Surfing Postdoc @mpipz.bsky.social with @hacquardst.bsky.social | Views are my own
339 followers226 following16 posts
Really happy how this turned out—and grateful for amazing collaborators 🙏 Thanks to all those who made this happen. Most of all Hannes Kramml (congratulations on an amazing PhD paper) and Wolfram Weckwerth at mosys.univie.ac.at 14/14
A side project that got out of hand—in the best way 🚀 New paper is out: www.nature.com/articles/s41... We sequenced the first Clusia genomes to understand something subtle but fundamental: 👉 CAM is a drought adaptive mechanism in plants - how do different physiotypes of CAM evolve? A 🧵 👇 1/14
A side project that got out of hand—in the best way 🚀 New paper is out: www.nature.com/articles/s41... We sequenced the first Clusia genomes to understand something subtle but fundamental: 👉 CAM is a drought adaptive mechanism in plants - how do different physiotypes of CAM evolve? A 🧵 👇 1/14
A side project that got out of hand—in the best way 🚀 New paper is out: www.nature.com/articles/s41... We sequenced the first Clusia genomes to understand something subtle but fundamental: 👉 CAM is a drought adaptive mechanism in plants - how do different physiotypes of CAM evolve? A 🧵 👇 1/14
A side project that got out of hand—in the best way 🚀 New paper is out: www.nature.com/articles/s41... We sequenced the first Clusia genomes to understand something subtle but fundamental: 👉 CAM is a drought adaptive mechanism in plants - how do different physiotypes of CAM evolve? A 🧵 👇 1/14
A side project that got out of hand—in the best way 🚀 New paper is out: www.nature.com/articles/s41... We sequenced the first Clusia genomes to understand something subtle but fundamental: 👉 CAM is a drought adaptive mechanism in plants - how do different physiotypes of CAM evolve? A 🧵 👇 1/14
A quick RECAP: CAM (Crassulacean Acid Metabolism) is a drought adaptation 🌵 Plants fix CO₂ at night, store it, and use it during the day → saving water. But importantly: CAM is not binary. 👉 It exists as a spectrum of physiotypes. en.wikipedia.org/wiki/Crassul... 4/14
A side project that got out of hand—in the best way 🚀 New paper is out: www.nature.com/articles/s41... We sequenced the first Clusia genomes to understand something subtle but fundamental: 👉 CAM is a drought adaptive mechanism in plants - how do different physiotypes of CAM evolve? A 🧵 👇 1/14
Most people know Clusia as an IKEA plant 🌱 But in nature, it’s a remarkable system: species span a continuum from C3 → weak CAM → strong CAM 👉 a living gradient of photosynthetic strategies. www.ikea.com/de/de/p/clus... 2/14
Johannes Herpell reposted
Great to see this really cool story (see quoted post) published in @newphyt.bsky.social! nph.onlinelibrary.wiley.com/doi/full/10.... Congratulations @laravdijck.bsky.social, @parkergroup.bsky.social! Plant-Scopoletin-Fungal Endophyte-Iron #PlantScience #Coumarin #PlantImmunity #PlantNutrition
This is such a cool story! ➡️ Arabidopsis produces scopoletin to fend off pathogens. ➡️ The beneficial M. phaseolina converts scopoletin to esculetin, thus evading its negative effects & out-competing pathogens. ➡️ Esculetin serves as iron-chelating coumarin to support the plant. #PlantImmunity
Johannes Herpell reposted
How can we better understand the plant immune system? In my new @cp-cellhostmicrobe.bsky.social piece, I propose “immune cell states” as a framework for uniting molecular and cellular perspectives. www.cell.com/cell-host-mi...
Johannes Herpell reposted
Fascinating innate immune evasion strategy in SCIENCE #glycotime 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘴𝘺𝘳𝘪𝘯𝘨𝘢𝘦 makes GLYCOSIRIN, a novel iminosugar that blocks plant glycosidases from degrading bacterial flagellin—hiding pathogens from plant immune sensors. New cryo-EM insights reveal exactly how this stealthy trick works
Johannes Herpell reposted
Nature research paper: Low overlap of transcription factor DNA binding and regulatory targets https://go.nature.com/4jedGUz
Would you like to study metabolite-based microbe-microbe or plant-microbe interactions but do not have the tools to? @chesneau-g.bsky.social came up with a simple solution with great potential! Check out our new publication in @naturecomms.bsky.social and Guillaume’s 🧵 below for details👇
🚨Excited to share our new publication! MetaFlowTrain, a highly parallelized and modular fluidic system to study exometabolite interactions between microbes-microbes-plants 🌱 @hacquardst.bsky.social @herpell.bsky.social S.Wolf S.Perin @mpipz.bsky.social www.youtube.com/watch?v=gNUf... 🧵Thread 5/5:
Johannes Herpell reposted
📣Paper Alert! 📣New publication out by @hacquardst.bsky.social and his team on the development of MetaFlowTrain – a new tool to study metabolic exchange and interactions within microbial communities @naturecomms.bsky.social 👏🥳Congratulations! 👉https://bit.ly/44jnM1H www.nature.com/articles/s41...
Johannes Herpell reposted
We present MetaFlowTrain, an easy-to-build, highly parallelized, and cost-effective fluidic system for studying microbial exometabolites and their roles in modulating microbe–microbe–host interactions. Kudos to @chesneau-g.bsky.social @mpipz.bsky.social Give it a try: www.nature.com/articles/s41...
Johannes Herpell reposted
How did horses become so athletic? In part, a mutation that should have cut a key protein short instead makes it more sensitive to the stress of exercise. That and more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪🐴
Johannes Herpell reposted
Finally! Im so excited to present to culmination of many years of work from the fantastic Defeng Shen and some great collaborators. For details, I have made a digested thread below, but if you are more interested feel free to reach out (and read the paper of course). www.science.org/doi/10.1126/...
Johannes Herpell reposted
📣Paper Alert! New publication @science.org by the group of @tonnigrubeandersen.bsky.social @mpipz.bsky.social, colleagues @ucph.bsky.social & others on the Casparian strip and its role in metabolic trade between plants & bacteria. 👏Learn more 👉https://bit.ly/4bJe4Yd www.science.org/doi/10.1126/...
Johannes Herpell reposted
We're looking for a postdoc to join the lab to work on cell-to-cell communication via the apoplast. Candidate must be brave, as they will have to lead us (me) away from the plasmodesmata-lands we've inhabited for so long! www.jic.ac.uk/vacancies/po...
Johannes Herpell reposted
Poke bacteria with a sharp needle and they poke back in just a few seconds! Congratulations to Mitchell (and others) for this analysis of Pseudomonas #T6SS assembly in response to membrane damage! Collaboration with Rod Lim's lab @biozentrum.unibas.ch www.science.org/doi/10.1126/...
Johannes Herpell reposted
🧪 Homo erectus crafted specialized tools out of the bones of elephants and hippos. Read all about it in my latest for Nature. #scicom #paleo www.nature.com/articles/d41...
Johannes Herpell reposted
Wow, cAMP production appears to be the key for activating canonical auxin signalling, not AUX/IAA degradation! Also annoying - I need to revise quite a many teaching slides to update auxin signalling 😀 www.nature.com/articles/s41...
Johannes Herpell reposted
🚨New paper published in @nature.com! Using pan-genetics across the Solanum genus🍅🥔🍆we reveal why gene duplications🧬are major contingencies in crop engineering. My postdoc work in the Lippman lab @CSHL, collab. with @katiejenike.bsky.social @mikeschatz.bsky.social chatz.bsky.social and many others!
Johannes Herpell reposted
📌Vacancy at the University of Amsterdam! Join us at the Green Life Sciences with three open positions by my colleagues. 🌱🌻 1/3 PhD position on "Microbial Host Preference in Plant Stress Resilience" in the group of Dr. Kathrin Wippel: werkenbij.uva.nl/en/vacancies...
Johannes Herpell reposted
Congratulations to Jana Ordon and all coauthors!!! Our new study is published in @natureplants.bsky.social "Conserved immunomodulation and variation in host association by Xanthomonadales commensals in Arabidopsis root microbiota" (0/n) rdcu.be/eauzt
Johannes Herpell reposted
Please read here about our collaborative work with Ag Kudla @uni-muenster.de on the phosphocode of these two Calcium-dependent kinases. With the power of MS-based functional #proteomics www.science.org/doi/10.1126/...
Johannes Herpell reposted
Happy to share this viewpoint, written together with @fabriceroux7.bsky.social and Fabienne Vailleau @lipme-toulouse.bsky.social nph.onlinelibrary.wiley.com/doi/10.1111/... 1/4
Johannes Herpell reposted
I’m super happy to have a great part of my PhD work (under the wonderful supervision of C. Libourel @pierremarcdelaux.bsky.social & @maximebonhomme.bsky.social) now out in @naturegenet.bsky.social ! Here’s a little thread (1/18) www.nature.com/articles/s41...
Johannes Herpell reposted
We continue to build the Plant Microbiome Starter Pack. Please let us know if you or others are missing! go.bsky.app/QG4wCyf
Johannes Herpell reposted
Have a look at our new story on how Bacterial Cellulose works miracles in plant wound healing by activating regeneration via concurrent activation of ROS, defense and cytokinin signalling. In collaboration with @cbgpmadrid.bsky.social @icmabcsic.bsky.social www.science.org/doi/10.1126/...
Johannes Herpell reposted
🔊Paper Alert - New publication out @nature.com by the Parker Lab @mpipz.bsky.social and colleagues at Westlake University on the fine tuning of plant immunity regulation 🌿🪴Congratulations 👏 👏 Learn more here 👉 bit.ly/3WZjrfw #plantsci #immunity www.nature.com/articles/s41...
Johannes Herpell reposted
Evolution of interorganismal strigolactone biosynthesis in seed plants www.science.org/doi/10.1126/...
Johannes Herpell reposted
I'm very happy to report that Matt Schechter's PhD work is now online as a pre-print: "Ribosomal protein phylogeography offers quantitative insights into the efficacy of genome-resolved surveys of microbial communities", www.biorxiv.org/content/10.1... Here's a little 🧵 about it.
Johannes Herpell reposted
Inspired by @mads100tist.bsky.social I'm going to do threads on parts of the publishing process we often get asked about. These will be from my perspective @naturecomms.bsky.social and based on my own opinions, so keep your salt handy.
Johannes Herpell reposted
The data is in. 2024 was the warmest year on record, and probably in the whole of human history – about 1.6°C warmer than the pre-industrial period. More than 1 billion individual thermometer measurements have been condensed into a single vital number. theconversation.com/my-new-dark-...
Johannes Herpell reposted
#weekendreading 🔬 Non-adapted bacterial infection suppresses plant reproduction in Science Advances #microsky www.science.org/doi/10.1126/...
Johannes Herpell reposted
The protein GAME15 is the missing link in the pathway that Solanum plants like potatoes use to make molecules for pest defense, a new Science study finds. The results pave the way for innovative applications in agriculture and biotechnology.
Johannes Herpell reposted
"[My adviser] told me that instead of focusing on finding a dream job, I should think about what I am good at and what makes me happy at least 80% of the time. This advice surprised me at first, but it ended up being exactly what I needed to hear." scim.ag/3DHtLCc
Johannes Herpell reposted
New year, new paper! Now published in @nature.com. We identified and characterised diverse immune cell states in plants under pathogen attack. My postdoc work in the Ecker lab at @salkinstitute.bsky.social. A thread (0/n) #PlantScience www.nature.com/articles/s41...
Johannes Herpell reposted
OUT NOW - Streptomyces secretes a siderophore that sensitizes competitor bacteria to phage infection www.nature.com/articles/s41...
Johannes Herpell reposted
Johannes Herpell reposted
Towards community-driven visual proteomics! Excited to finally share this large-scale curated & annotated dataset of 1829 high-quality #cryoET tomograms of the little green alga that just keeps giving— Chlamydomonas! 🧪🧶🧬🌾🌊🌍 Preprint📜: www.biorxiv.org/content/10.1... A short thread🧵👇
Johannes Herpell reposted
We are still waiting for applications to join us as a group leader in the department of Chromosome Biology! Apply until the first of Feb.
The department of Chromosome Biology of the Max planck @mpipz_cologne is looking for a new group leader. Join us, with @Polina_Novik @marques_et_al @LabSchneeberger We are very open minded concerning the project, it just needs to be exciting. jobs.mpipz.mpg.de/jobposting/8...