kitchensinging.bsky.social reposted
kitchensinging.bsky.social
kitchensinging.bsky.social
@kitchensinging.bsky.social
Nobody's home and I'm going to sing now
79 followers165 following333 posts
kitchensinging.bsky.social reposted
kitchensinging.bsky.social reposted
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kitchensinging.bsky.social reposted
Replying to @errantv.bsky.social
LLMs don't work for biology because sequence doesn't predict structure. The absolute best they can do is plagiarize a known functional sequence, they can't make a new discovery. Until we get enough compute (i.e. quantum computing) to do physics models, ML will be near useless in drug discovery.
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Ayup. I work in antibody discovery in big pharma our hit rate for in vivo & in vitro screens is ~60% I've screened over 10k predicted molecules from partners at the big AI labs in SF this year. They have produced a total of 2 hits, both of which were plagiarized from molecules on the market already
My thoughts on how frontier AI’s claims and warnings seem prone to colliding with reality, whether that’s in economics, medicine or cyber security ciaranmartin.substack.com/p/on-ai-clai...
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lol owned
I wish all Afrikaner "refugees" a very pleasant "fall off your bicycle and find out how much a sprained wrist costs in America"
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Since the story about the AI kill chain is circulating, this interactive study produced thru a collab between Airwars and AI Now in July is an excellent companion read. ai-killchain.airwars.org
HUGE EXCLUSIVE from @bloomberg.com Inside the US ‘Kill Chain’ That Destroyed an Iranian School Pentagon investigators discovered that flawed intel, outdated imagery & overreliance on AI contributed to a missile strike that killed 123 children in Minab 🎁 www.bloomberg.com/graphics/202...
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this whole thing is madness inducing but the middle paragraph here is the one that made me say "oh we're FUUUUUCKED fucked" out loud
A few weekends ago I went to Miami and attended 9 open houses in extremely high-risk flood areas to see what agents are telling prospective buyers about them. Here is my journey
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Replying to @spavel.bsky.social
"Moved files onto the open internet without permission" is also literally just hallucination. We've known since 2022 that these things do shit you ask them not to do, and that this is a fundamental flaw of the architecture that can never be fixed So they're correcting it with marketing instead
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The first gov't agency to realize Oracle is worthless will have a hundred-year reign
Case in point: a while back, Mamdani announced the creation of a tech office to improve government services. For people who cover govt and tech, this was a legitimately big story. Mamdani even held a press conference and made staffers available for comment. donmoynihan.substack.com/p/mamdani-in...
post something random or you'll have an awful September youtube.com/shorts/d8M4N...
As a former ELL teacher, I accept truly any comprehensible pronunciation unless a student aims for more. But I will NEVER accept the hundred contradictory raving mad phonics systems Anglophones bludgeon learning readers with when IPA is right there.
macabre = “muh-KAHB” Worcestershire = “WOOSS-ter-sheer” omnipotent = “ahm-NI-puh-tunt” reticent = “RET-uh-sunt” epitome = “ih-PIT-uh-mee” myriad = "MEER-ee-ud" Never make fun of someone if they mispronounce a word. It means they learned it by reading.
As someone involved in a public works project outsourced to a private equity firm in a construction suit, I can vouch that it’s all like this, all the time
A former Navy cleanup contractor will pay $57 million to resolve allegations that workers falsified environmental testing data during the cleanup of San Francisco’s Hunters Point Naval Shipyard.
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Replying to @70sbachchan.bsky.social
You can't predict the turns this sentence takes. Extreme heat is threatening Italy’s “cheese banks,” where hundreds of thousands of Parmigiano-Reggiano wheels are stored as loan collateral. fortune.com/2026/08/10/i...
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Embrace American Gentry Thought www.theatlantic.com/ideas/archiv...
Most rural areas have a ruling class. And they want cheap unfree workers & to pass their fiefdoms on tax-free forever. It ain't rocket science. The fact that we're scared to talk about THAT, ime, is what's costing us a lot of rural voters!
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Replying to @taylordahlin.com
john hoffman, MN state senator who survived an assassination attempt by vance boelter, who killed mark and melissa hortman, is here supporting omar fateh. he said fateh was his first visitor when he was in hospital. gave him a note saying “we’ll get that fucker” that is still on his fridge
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Replying to @quantian.bsky.social
Fable concludes that an untrained adult would throw a naan further as there's sufficient membrane tension to stop folding. A baguette javelin would theoretically go further but is too unstable to maintain flight and would start tumbling unless you could add spin-stabilization or fins.
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This is the first time I’ve ever seen a CA publication speak plainly about both the stakes (and the basic distributional politics involved) The FAIR plan is a ticking time bomb and the primary problem is it promises to insure uninsurable property for rich people. www.latimes.com/business/sto...
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Reporting on OMB's sweeping politicization of federal grants tends to focus on science / health research. But as I note in this piece for @crisesnotes.bsky.social, the rule is a huge threat to *intergovernmental* grants and state/local fiscal stability. www.crisesnotes.com/russell-voug...
The increasing adoption of Flock into America's PD has foreseeable escalation and death risks
As noted in this LAPD audit, when a car is put onto a hotlist and there's a hit, the cops go into the situation expecting a confrontation. These are by definition "high risk" stops that are highly dangerous for the person being pulled over