Emma Harding

Emma Harding

@emma-harding.bsky.social

Postdoc at Oxford University researching paleovirology, virus evolution and the global virome πŸ‡¦πŸ‡Ί πŸ‡¬πŸ‡§

666 followers1.1K following23 posts

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Hello bluesky! I'm a postdoc in evolutionary and computational virology. I'm interested in finding new viruses and tracing their evolutionary history using endogenous viral elements. πŸ§¬πŸ§‘πŸ»β€πŸ’» In general be posting about virology, popular science and life as a scientist.

Emma Harding reposted

Recently, there was quite a furore in Australia's parliament about invasive species management. It seemed to me there was some misunderstanding about terminology & the very important reasons for controlling some introduced & invasive species. So, I wrote this πŸ‘‰ theconversation.com/calling-spec...

theconversation.comCalling species β€˜invasive’ – and culling them – isn’t done lightly. But it matters to Australia’s threatened speciesInvasive species only want to live. But their success can come at great cost to native species. If we treat them the same, native animals lose.

Emma Harding reposted

🌬️ New paper out in Environmental DNA! We developed a 3D-printable passive airborne eDNA sampler and tested practical sampling parameters. 🧬 Smaller filters performed better than expected! ⏰ Sampling duration matters! πŸ“¦ Signals are robust to short-term storage! πŸ”— doi.org/10.1002/edn3...

Excited to announce our newest paper πŸ“š where we explore alpharetrovirus envelopes co-opted multiple times across bat lineages πŸ¦‡

Aris Katzourakis@ariskatzourakis.bsky.social

Our paper on the enigmatic alpharetrovirus lineage in bats is out! Huge credit to @emma-harding.bsky.social, and of course all co-authors involved in helping experiment, draft, analyse and discuss. @biology.ox.ac.uk @ox.ac.uk #paleovirology journals.plos.org/plosgenetics...

Emma Harding reposted

Emma Harding reposted

Emma Harding reposted

Emma Harding reposted

Our two-part analysis of the current MV Hondius Andes virus outbreak is now live, including reconstruction of the outbreak molecular clock dating of the closest known ancestors of the outbreak lineage. Part 1: outbreak sequence reconstruction and rooting virological.org/t/molecular-...

virological.orgMolecular evolutionary analysis of the current MV Hondius Andes virus outbreakPreliminary reconstruction of the current MV Hondius Andes virus outbreak sequences Note on data use This is an informal analysis of currently available consensus sequences and is not intended as a fo...

Emma Harding reposted

It is almost five years since I first applied AlphaFold to a handful of viral proteins. Today, hundreds of thousands of predictions and many discoveries later, we are delighted to announce the integration of our Viro3D dataset into the @ebi.embl.org and Google DeepMind AlphaFold Database.

EMBL-EBI@ebi.embl.org

The AlphaFold Database, jointly developed with Google DeepMind, now contains datasets from specialist communities. This includes rich datasets for microbes, viruses & parasites associated with tropical diseases. Explore the new datasets in the AlphaFold Database. www.ebi.ac.uk/about/news/u...

Emma Harding reposted

Emma Harding reposted

Proposing targetted culls of sharks is a nonsense & demonstrates Dr Adam Smith is ignorant about shark life history, ecology & behaviour, & changing the statistical probability of exceedingly rare events. Sharks behave nothing like kangaroos, koalas & starfish. au.news.yahoo.com/calls-grow-f...

au.news.yahoo.com'Too many sharks': Calls grow for controversial experiment in Aussie watersAustralia is searching for answers following four shark attacks.

Emma Harding reposted

The retrovirome of each amphibian class is very different - caecilians can harbour the widest diversity of retroviruses whilst frogs and toads harbour the least 🐸 Two caecilian retroviruses are more similar to bird πŸ¦β€β¬› and mammal viruses than to other amphibians - a drastic host jump!

We also find that ancient viruses, now embedded in amphibian genomes as endogenous viruses, are surprisingly active after millions of years 🦴⏱️ Lastly, we note that some endogenous retroviruses exist as thousands of copies within a genome 🧬 - a significant mutational burden left unchecked.

Emma Harding reposted

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Emma Harding reposted

Save the date - don't miss out! The 72nd Australian Mammal Society Conference will be held in Canberra (Shine Dome) from 5th - 10th July 2026! This very special conference will be jointly held with the #australasianbatsociety - ECR workshops on 5th - focussed #bat and #dasyurid symposia on 6th πŸ¦‡πŸΎπŸ­πŸ¨

HI-FEVER scans host genomes for endogenous viral elements (EVEs), reconstructs the ancestral viral protein and predicts it's classification. πŸ§¬πŸ”βœ”οΈ The best part: it runs on everything from small laptops to HPC computers needing as little as 5GB storage space (including databases!).

Emma Harding reposted

Emma Harding reposted

Haunted lately by @galaxyproject.bsky.social COβ‚‚e estimates for jobs. This one MEGAHIT assembly: ~450g CO2e. I've run this ~150k times on HPC, ~75 tonnes of CO2e 😬. Perhaps ARC/NHMRC would accept Australian Carbon Credit Units as part of the grant cost for offset? What others are doing in AUS/INT?

Do you research endogenous retroviruses (ERVs) or want to learn more about them? πŸ§¬πŸ€” Consider presenting at or attending AuusiERV - an inaugural online symposium for ERV research in Australia πŸ‡¦πŸ‡Ί (and abroad) πŸ—ΊοΈ Abstracts due 1st October! events.humanitix.com/aussierv-2025 #ERV #retrovirus

events.humanitix.comAussiERV 2025AussiERV: Australia’s first symposium dedicated to endogenous retroviruses. Join us for this one-day virtual event on November 7th!

Emma Harding reposted

🚨 Proceedings B is recruiting new Data Editors! Join our editorial board to help ensure data/code transparency across biology. πŸ—“ Term: 3 yrs from Jan 2026 πŸ“© Apply by 30 Sep 2025 with a 2-page CV + cover letter: proceedingsb@royalsociety.org πŸ”— Info: jackbrand.work@gmail.com /dylan.ge.gomes@gmail.com

Emma Harding reposted

This is the first evidence of endogenous deltaviruses within animal genomes. 🧬 We also find a deltavirus that has become part of a host gene, fusing with a nucleoplasmin as part of a co-option event! πŸ§¬πŸ«‚ #deltavirus #virus

Whilst in humans deltaviruses like hepatitis D virus need a helper virus to infect cells, we didn't find any evidence of a helper in termites. They may transmit directly through feeding or vertically from the queen, but further research on this will help us understand how satellite viruses work πŸ€”