@KingOfPathogens

Anyone interested in the immune response to enteric infections? You are welcome to gutpath.org and this www.nature.com/articles/s41... @aai.org @cytokinesociety.bsky.social

For those in the mood for some seriously well-done gallows humor, I heartily recommend this... inpreparation.substack.com/p/nih-simpli...

This may never be topped.

We've been quiet, but we've been busy! Delighted to share that in recent weeks we have received 3 NIH R01s to continue our studies of adaptive immunity in the gut! As such, we are recruiting post-docs with strong interests and expertise in mucosal immunology and antigen-specific T and B cell 1/3

Helen Stillwell in the Weiss lab defends her thesis tomorrow!

Seems timely www.nytimes.com/2026/08/12/w...

@biorxivpreprint.bsky.social A Cytokine Receptor Signaling Atlas Reveals How STAT Mosaics Fine-Tune T Cell Function www.biorxiv.org/content/10.6... @stanforduniversity.bsky.social

eww but also fascinating research that could give a clue as to why a normally harmless pond-dwelling amoeba can turn into a deadly brain eating parasite if infects us. Looks like it preferentially looks for narrow channels (but not too narrow) to live in and once in just keeps swimming.

For the lovers of Treg cells. What happens after the infection-induced loss of Treg cells and how is that compartment rebuilt. @cytokinesociety.bsky.social @aai.org @britsocimm.bsky.social onlinelibrary.wiley.com/doi/10.1002/...

"Institutions must avoid a dangerous and emerging misconception: that academic research should be financially self-sustaining. Historically, society has not expected classical music to justify its existence through commercial profitability, and neither should it expect fundamental science to do so."

Careful debunking of the misinformation that Trump and RFKJr touted in the press conference for Trumps wish to reduce the number of free vaccines available

I love this bacterial immunity field, it’s so cool! The bacteria have already done all the cool #innateimmunity pathways

The man's skeletal injuries looked like a train hit him, but he died in 1304 CE. At #ppa26Berlin last week, @uniofbradford.bsky.social scientist Jo Buckberry concluded he was likely whacked by a flying boulder, making him the first confirmed trebuchet death in the archaeological record. @science.org

I’m tired of having to say cyclosporida or spell clyclosporiasis. Repurposing the longtime favorite “gastrocatastrophe” and adding “the old Clyclo” to the mix. Maybe “they got cyclosped” or “just a touch of the clospors” to keep things interesting.

Fluid shear stress as a co-stimulatory cue to enhance T cell priming and restore activation in cancer patient T cells @J_Immunol academic.oup.com/jimmunol/art...

a legend in our understanding of how remarkable our immune system is

I am so proud to be apart of @societymucosalimm.bsky.social. Everything I do for the @mucosalimmunol.bsky.social journal and podcast, I do to learn and share all of the amazing science🧪 from the many fantastic researchers 👩‍🔬 in this community. Thank you 💚 #ICMI2026

I wonder, if at any point during the 10 years of The Odyssey, at any point, did any of the crew ask "Are we there yet?" Keep that in mind when watching the movie #ChristopherNolan #MattDamon #Odyssey ........

Do you live in Philly? Has your cat been acting crazy? Well, it is likely this craziness is not due to H5N1 infection--but rather the fact that your cat is a cat. In this new preprint with @lhmoncla.bsky.social we find low H5N1 seroprevalence rates in Philly cats. www.biorxiv.org/content/10.6...

I posted this 2 years ago prior to the 2024 election. They really spelled it out, and enough Americans were fine with it to let this horror show proceed. We're over halfway there. What a disaster. #Project2025

#Science #Immunology turns 10 years old this month! We celebrate w/ a Special Issue on immune #memory! Check out our 3 outstanding Reviews by Maziar & Kaufmann; @sjturn.bsky.social, Thiele, & @niclag.bsky.social; & @maurogaya.bsky.social & @kimljacobson.bsky.social out this week! scim.ag/448rEkV

Review @jimmunol.bsky.social @kingofpathogens.bsky.social Getting on your last nerve: IFNs and resistance to infection academic.oup.com/jimmunol/art...

There are so many tech companies now named after Lord of the Rings (Palantir, Anduril, Earendil…) Very concerned that in 20 years tech will be disrupted by Hufflepuff Industries

Congrats to the new @bwfund.bsky.social Path awardees! It was an incredibly strong applicant pool, so thanks also to the selection cmte for their thoughtful work and my co-chair @kingofpathogens.bsky.social. Many applicants apply multiple times before being selected so don’t hesitate to reapply!

NIAID employees did not receive any communication about these leadership changes until this afternoon, when the institute sent out an unsigned email.

BWF Announces the 2026 Investigators in the Pathogenesis of Infectious Disease www.bwfund.org/news/bwf-ann... #bwfpath

Despite general systemic immune modulation during reproduction, the maternal intestine undergoes remodelling to strengthen innate defense to protect mothers & offspring from pathogens @nature.com @princeton.edu @aiinglim.bsky.social www.nature.com/articles/s41... www.nature.com/articles/d41...

It’s still unclear whether Hantavirus is scary enough to guarantee 1,000 publications in Nature

I would like to announce that I was this year's recipient of the Hunter Lab best kept desk award! Award ceremony will be in Stockholm. www.theguardian.com/world/2026/m...

More than thrilled to share that I’ve been promoted to full (tenured) Professor @harvardmed.bsky.social @harvard.edu! This only happened because of the hard work of many people, but I want to dedicate this promotion to my grandmas, Nonna Maria & Nonna Vevè. A #FirstGen thread 🧵 1/x

The latest MI Podcast episode is out - get excited for #ICMI2026 with @kinglabmcgill.bsky.social, learn about IL-36 with @ryanthwaites.bsky.social, and more! www.iheart.com/podcast/269-...

My thoughts on Director Bhattacharya's Fireside Chat at the NAM workshop (a long 🧵) Overall (1) He clarified what he said that NIH is doing with regard to improving replication. While these are concrete steps, they seem either naive or dependent of unproven technology. Time will tell. 1/30

Had a great time talking C. diff on the #MattersMicrobial podcast! Thanks so much to @markowenmartin.bsky.social for being such a fantastic host and for the great conversation!

My kids have measles, I can't afford gas, and I'm going to be dead within 2 years now that the CDC cancelled funding for the mRNA treatment that might have save my life. But at least now we have Secretary of War who is a Pulp Fiction fan.

Peripheral vaccination-induced brain-resident memory CD8+ T cells durably protect mice against intracranial malignancy @jci.org www.jci.org/articles/vie...

Except in GCs theonion.com/biologists-c...

events.nyas.org/autoimmune1

@biorxivpreprint.bsky.social The role of integrins in T cell-mediated resistance to Cryptosporidium parvum www.biorxiv.org/content/10.6... @i3h-upenn.bsky.social @kingofpathogens.bsky.social

For those interested in T cell trafficking to the gut - maybe LPAM is not so dominant during enteric infection... www.biorxiv.org/content/10.6...

Statistically significant chuckles: who is using humour at scientific conferences? url: royalsocietypublishing.org/rspb/article...

Happy to share this study from the lab led by Orlaith Keenan published in mBio! Working with an outstanding collaborative team, Orlaith demonstrated that maintaining the right balance of neutrophils is key to limiting severe disease during C. difficile infection. journals.asm.org/doi/10.1128/...

Watch Director Bhattacharya's performance at CPAC really got to me. I chose to share some of my observations with him. Hold on... 1/11

Ending the war between the US and Iran will be hard, experts say, due to the difficulty of negotiating with a weak, erratic head of state.

Out Now! A global-scale assessment of zoonotic virus diversity and spillover potential in urban-adapted mammal species #MicroSky

Vaccine Engagement Day 2026 has arrived! 🎉 Let’s come together to #CelebrateVaccines by sharing information and enhancing public awareness about vaccines!🌟 Discover how you can participate: vist.ly/4v2vi

Awe inspiring talk last week as Fauci reflects on 40 years of the AIDS pandemic. @aai.org www.vet.upenn.edu/anthony-fauc...

One for the parasitologists AND cytokine engineers - creative use of a worm TGF to modulate the immune system. www.nature.com/articles/s41... @cytokinesociety.bsky.social @aai.org @bes-parasitesgroup.bsky.social