Mathilda Lennartz

Mathilda Lennartz

@mathilda95.bsky.social

| Lipids | Membranes | Ichthyosporea | How do lipids facilitate multicellularity? Postdoc @ Dudin (UNIGE) & D'Angelo (EPFL) labs

269 followers229 following23 posts

Mathilda Lennartz reposted

This is a great opportunity. Do apply - Falk is an all-around great guy!

Falk Schneider@faldalf.bsky.social

1/5 🚨 🔬 PhD opportunities in my lab at @uni-of-warwick.bsky.social What is the role of plasma membrane organisation in tissue formation? Let’s find out! www.findaphd.com/phds/project... I’m recruiting for several interdisciplinary PhD projects. #PhD #Biophysics #Microscopy ⬇️ Details below 🧵⬇️

Finally, a huge thanks to the Honigmann, Modes, Šachl, Opálka, and Hof labs for this amazing team effort. And of course thanks to the facitilies of @mpi-cbg.de: the LMF, the GEF, and the scientific computing facility 😀.

This revealed that while clathrin-mediated endocytosis is highly selective towards protein cargo, it is largely non-selective for all the lipids tested in this study. If that’s for you, check it out! (we also added a lot of cool new datasets since the bioRxiv upload 😉: bsky.app/profile/nadl...).

André Nadler@nadlerlab.bsky.social

Are lipids actively sorted during clathrin mediated endocytosis like proteins? @mathilda95.bsky.social addresses this key open question together with our collaborators from the Honigmann and Modes labs using a new Lipid-STED workflow. www.biorxiv.org/content/10.1...

Mathilda Lennartz reposted

People!!! This workshop will be ACE - please share, please apply!

The Company of Biologists@biologists.bsky.social

Applications are now open for early-career researchers to apply for a funded place at our Workshop on Membrane Function: Insights from Cellular Diversity and Evolution, organised by Snezhana Oliferenko @alebenoit.bsky.social & Cunqi Ye. Find out more and apply www.biologists.com/workshops/ju...

Mathilda Lennartz reposted

Very proud of the team, led by @baukjeje.bsky.social & @fmikus.bsky.social To all of you doing #Expansion #Microscopy #UExM Try Concanavalin A. Its cheap, easy to use & labels the #nuclear #Envelope @moorefound.bsky.social @embl.org @sciencesunige.bsky.social @erc.europa.eu @snsf.ch

Baukje Hoogenberg@baukjeje.bsky.social

Do you want to label the nuclear envelope? Do you work on a non-model species? Try Concanavalin A! We tested ConA on various species across the eukaryotic tree and find it is a very useful ExM-compatible marker for the NE and ER. Read all about it in our preprint: www.biorxiv.org/content/10.6...

Mathilda Lennartz reposted

Mathilda Lennartz reposted

Mathilda Lennartz reposted

Now out in its final form in @jacs.acspublications.org: Reaction pathways & photoreaction yields of bifunctional lipid probes. The numbers that explain why we spend so much time optimizing protocols for cellular assays. 😉 pubs.acs.org/doi/10.1021/...

pubs.acs.orgBifunctional Lipid–Protein Cross-linking Efficiency and Reaction ProductsBifunctional diazirine lipids are versatile tools for mapping protein–lipid interactions and cellular localization by photo-cross-linking. Yet, the cross-linking efficiency of these probes has not bee...
André Nadler@nadlerlab.bsky.social

It's always important to carefully characterize the reactivity of your favorite tools to optimize applications. We teamed up with Carla Kirschbaum and Carol V. Robinson to map photolysis reaction pathways of bifunctional lipids www.biorxiv.org/content/10.6...

Mathilda Lennartz reposted

We offer a PostDoc position for a fully funded project on lipid-encoded #lipidtime protein quality-control checkpoints at the Golgi: great collaborators, excellent working & living conditions & benchspace with a view ;) Please share and repost!

Mathilda Lennartz reposted

Mathilda Lennartz reposted

Mathilda Lennartz reposted

This is amazing! My mind is boggled. Congrats to the whole team.

Yamuna Krishnan@krishnanyamuna.bsky.social

Organelles do NOT have a single uniform pH. And if you think they must, because “protons diffuse fast,” this paper is for you. A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

Finally out! This is an amazing story on lipid trafficking and how to visualize membrane lipids inside of cells! Check it out. I am honored I could contribute a little to this story 😁

André Nadler@nadlerlab.bsky.social

Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism. www.nature.com/articles/s41...

I am really excited that the second story of my PhD work is on biorxiv now. If you are into lipids, membrane trafficking and super resolution microscopy check it out! Big shout out also to our collaborators, the Honigmann lab and Modes lab.

André Nadler@nadlerlab.bsky.social

Are lipids actively sorted during clathrin mediated endocytosis like proteins? @mathilda95.bsky.social addresses this key open question together with our collaborators from the Honigmann and Modes labs using a new Lipid-STED workflow. www.biorxiv.org/content/10.1...

You are up to date.