Fabrice Senger

Fabrice Senger

@senger.bsky.social

Mechanobiology / Multi-cellular assemblies

844 followers387 following854 posts

Fabrice Senger reposted

It's fall, which means it's bioimage analysis conference season! @erinweisbart.bsky.social and @bethcimini.bsky.social had SUCH fun at the @bioimagingna.bsky.social/I2K #I2kxBINA2026meeting last month. We HAD to take advantage of being in person together to film on-site with our friends! (1/2)

youtu.beLive from I2K/BINA 2026: A Potpourri of Questions - Ask Erin Dear Beth Episode 43YouTube video by Ask Erin, Dear Beth
Ask Erin / Dear Beth@askerindearbeth.bsky.social

Image corrections might not be the answer to EVERYTHING, but in Ep 42, we discuss how they might be the answer to "improving your measurements enough to measure the thing you care about". @bethcimini.bsky.social and @erinweisbart.bsky.social discuss what, when, and why!

Fabrice Senger reposted

Septin cytoskeleton acts like intermediate filaments! Our & @pwoakes.bsky.social newest papers in @jcb.org show septins relieve mechanical stress, a key oncogenic trait that can help metastatic tumors survive. Exciting translational implications, a new player in mechanobiology, sick imaging!

New work from Mayca Pozo et al. @septinlab.bsky.social reshapes #septin biology: septins relieve #actomyosin forces, shielding #actin & the #nucleus from mechanical damage. SEPT9 overexpression may promote tumor cell survival by limiting genomic damage during #metastasis. rupress.org/jcb/article/...

Fabrice Senger reposted

The new ELLIS Unit in Grenoble will celebrate its kick-off on 8 December! Join them for scientific talks featuring ELLIS President Serge Belongie and Mirco Ravanelli from Concordia University. Participation is free! Programme & registration: https://bit.ly/4zC71LA

wonderfull poster and line-up

Al Jord Lab@aljordlab.bsky.social

Don’t miss next week’s symposium featuring leading speakers! 🔥 Hope to see you there ! #CellArchitecture #Evolution #Imaging @crg.eu @prbb.org @upf.edu

Fabrice Senger reposted

Fabrice Senger reposted

More on CCM, from a mechanical perspective

bioRxiv Biophysics@biorxiv-biophys.bsky.social

Letting go to hold on: loss of CCM2 disrupts endothelial force balance in cerebral cavernous malformations https://www.biorxiv.org/content/10.64898/2026.10.09.757835v1

Fabrice Senger reposted

Our work is finally out! How do organs get the right shape and size on time? Using the zebrafish inner ear canal, we show that a mechanical feedback loop between the ECM and Yap1 drives timely tissue growth, and a built-in termination system shuts it down once morphogenesis is done.

nature.comA self-limiting mechanotransduction feedback loop ensures robust organ formation - Nature CommunicationsDeveloping tissues must acquire the correct shape. This study shows that mechanical feedback between the extracellular matrix and Yap sustains timely tissue growth, while Adgrg6 terminates the feedbac...

Fabrice Senger reposted

Sounds interesting while the software is not released with the paper...

bioRxiv Biophysics@biorxiv-biophys.bsky.social

GENIE: a multi-agent system for closed-loop autonomous microscopy https://www.biorxiv.org/content/10.64898/2026.10.12.758370v1

Fabrice Senger reposted

Last days to apply and join my lab!👇

Estibaliz Gómez de Mariscal, PhD@gomez-mariscal.bsky.social

🚨I have open PhD positions in my new lab at #NIMSB🚀!! Deadline Oct-16 nimsb.unl.pt/join-us/ 🌟I'm looking for motivated candidates who are eager to join a highly multidisciplinary team and study the intracellular dynamics of cancer cell migration using advanced computational methods and microscopy👾

Fabrice Senger reposted

🔬 We're hiring a Laboratory Manager! Join our growing international team at the Max Planck Center for Physics and Medicine in Erlangen! 🧬 Cell & molecular biology 🧪 Lab coordination & experimental research 📩 Apply now: [https://www.fau-jobs.de/jobposting/8173a98034c48d53d57bce14503883cbdbf6f3b80]

Fabrice Senger reposted

Are you a biologist working with microscopy images? A computer scientist wanting to work with microscopy data? Their boss??? None of these, but curious how AI has transformed microscopy image analysis? 🔬🤖 This one's for you: 📄 doi.org/10.1146/annu... More in the thread! 🧵

doi.orgFrom Pixels to Discovery: Microscopy Image Analysis in the Age of Artificial IntelligenceModern microscopy generates data volumes that far exceed human analytical capacity. Over the past decade, artificial intelligence (AI) has transformed microscopy image analysis into an engine for quan...

Fabrice Senger reposted

The original #Luxar thread is way too long and most people missed most demos, so I will be slow-dripping demos in the next weeks... Here is how you can annotate anything drawn and have text, images, videos overlays displayed on-hover or links opened on-click!

Loïc A. Royer 💻🔬🧪@loicaroyer.bsky.social

Hover can show images too. The CytoSelf protein-localisation map from OpenCell: hover a protein and its source micrograph appears. Demo: demos.luxarviewer.dev/d/cytoself_...

Fabrice Senger reposted

The Marseille Imaging Institute invite you to its R&D Imaging Seminar, November 2–6, 2026, La Timone Marseille Join us for a week of academic & industrial talks covering: #NuclearImaging, #AI and imaging, #OpticalImaging, #MRI, #Ultrasound & #Xray imaging Infos & registration: shorturl.at/9tVJt

Fabrice Senger reposted

It’s dreadful outside so please help me succeed in getting good Persian rice. Knowledgeable people: what did I miss and how to get it right next time?

Fabrice Senger reposted

The power of funding fundamental discovery in driving unexpected benefits for humankind are unmatched. We should be funding more basic research not less

UCSF@ucsanfrancisco.bsky.social

UCSF’s Kevan Shokat, PhD, just won the $1M Stephenson Global Prize for research in pancreatic cancer. He cracked KRAS, a cancer driver long considered “undruggable.” Drugs built on his work now treat lung and pancreatic cancer. https://ow.ly/UYuY50ZRSXg