Michael Hoffman

I'm at Princess Margaret Cancer Centre and University of Toronto. We have three major interests: 1/Computational methods and #ML for gene regulation data 🧬🖥️ 2/Liquid biopsy beyond simple genetic variants (epigenomic, immunogenomic) 3/Reproducibility and robustness of biomedical analysis (esp. #ML)

Sorry about Jamaal Myers. He was good.

Deep breaths

Aaaaaa

The chorus of my adolescence.

Kevin Bacon is not the center of Hollywood. “In fact, he never has been, and almost certainly never will be.”

House Judiciary Democrats have just released a 50-page report that pulls together years of assault allegations against Trump and his reported connections to Jeffrey Epstein. The report calls for a special counsel to investigate Trump's ties to Epstein.

When I was a kid getting cancer was nearly guaranteed to be lethal. I knew one cancer survivor, and it was a very close call. Now every single one of us knows multiple people who have survived very serious cancers. Thank the NIH for funding basic science and clinical studies.

Local Wikipedia is cool edjefferson.com/localwiki/

Sugar Maple only got a majority in one ward. End the tyranny of first-past-the-post.

📣 UBC Science seeks a Black scholar for a tenure-stream Assistant Professor position in Quantitative Science, starting July 2027. 📅 Apply by Dec. 1, 2026 💻 Info sessions: Oct. 16 & 30, 10 am PT Apply and learn more: science.ubc.ca/blackscholars

Do you disavow the Sisterhood of the Travelling Pants?

0.38 Scaramuccis

oh no my ai went rogue and ordered another two margaritas for me at chilis happy hour

@jrossibarra.bsky.social

Johns Hopkins Biology is hiring a tenure-track Assistant Professor in computational genetics and genomics. Applications due Nov. 8th: apply.interfolio.com/194924 In my experience, this has been an incredibly supportive environment to build a lab. Please feel free to reach out with any questions.

Buh Theatles

ONE TYPE OF PERSON ON SOCIAL MEDIA: I don’t like AI THE OTHER TYPE OF PERSON ON SOCIAL MEDIA: Pretty naïve of you to say that when it just zip zorped the gringle in less than seven kleebs. SEVEN. KLEEBS.

The SPEAKER implies. The LISTENER infers. The DUDE abides.

Hey, I’m just asking questions. Ignorant questions, bigoted questions, questions that have been repeatedly answered for many years. Sorry, but I’m not listening to answers right now; I’m far too busy asking questions. It’s called being intellectually curious.

When I used to write for The Guardian, every time I wrote the word “meow” the editors would change it to “miaow”. It used to really get on my wick. Don’t try to make my cats sound like your upper middle class London cats, you fuckers. My cats did not go to your posh cat schools. They say “meow”.

sometimes I want to use the phrase 'as an empath' but I don't, because I know how it will make others feel

i think it may be conscious

From a discussion of updating a department website...

Excited to share that my department has an open faculty search for an Assistant Professor! The search is broad, focused on candidates who plan to address fundamental questions in genetics and genomics. The due date is soon: Nov 13. You can apply through interfolio. apply.interfolio.com/190644

[explaining social media to aliens] yeah you basically scroll a little screen for hours and get absolutely furious

BREAKING NEWS: “Do geese see God” is a palindrome

My department at University of Utah is recruiting new faculty, with "Human" and "Genetics" broadly defined. It is a fantastic place to start a lab, with collaboration, creativity and conviviality encouraged. Applications due Oct 16. Please share and apply! utah.peopleadmin.com/postings/208...

For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu

This is the master key to deciphering contemporary debates about free speech. www.lrb.co.uk/blog/2026/se...

Do not carry a cold beverage in their presence. Politely decline any drinks or sweetmeats they may offer. Keep a plain iron nail in your left trouser pocket and a sachet or paper twist of coarse salt in your right shoe. Enter and leave your chair moving clockwise. Follow up with a thank-you note.

The redone Front Campus @utoronto.ca without cars is so nice. I never would have imagined this space could be transformed into something so nice.

Exciting news: @uwgenome.bsky.social will be hiring for two tenure-track faculty positions this year, one open rank and one assistant professor. Both are “Genome Sciences” interpreted broadly so we welcome applicants working in a variety of fields and methods. Ad will be out shortly.

Hello friends, the Harvard Life Science departments have banded together to hire a new colleague working at the intersection of Life Sciences and AI. Could be primarily an experimentalist, or could be primarily a compute/theorist. academicpositions.harvard.edu/postings/16773

Trump's low approval numbers raise new questions about Joe Biden's ability to connect with voters.

Making it impossible for anyone outside Canada to know what time it is here is an important part of reinforcing Canadian sovereignty. www.cbc.ca/news/canada/...

10 years ago today @casey.greenelab.com launched our review "Opportunities and obstacles for deep learning in biology and medicine" greenelab.github.io/deep-review/. It was a widely collaborative project written on GitHub, which lead to the creation of manubot.org.

@casey.greenelab.com

found at ucsf

Pls share: Princeton has an open rank faculty search in the areas of cancer biology, cancer prevention, and cancer-relevant computational science, including connections between cancer and immunology or metabolism. apply.interfolio.com/191852

BCB is recruiting a senior faculty member! We seek internationally recognized candidates at the Full Professor level with outstanding records of solving broad biological problems. Learn more and apply here: apply.interfolio.com/192850

every few months I have reason to send Ricki Heicklen's collection of unparalleled misalignments (e.g. "butt dial" and "booty call" are composed of synonyms but are not, per se) to someone and I get to look at what's been updated since and it never fails to delight rickiheicklen.com/unparalleled...

The newly established Department of Systems Biology (systems.bio.uci.edu) @UCIrvine is hiring a tenure-track Assistant Professor in Systems Biology. Great science, incredible faculty support, and beautiful, sunny SoCal weather! ☀️🌴 Details: recruit.ap.uci.edu/JPF10377. Please share.

This man won his primary by 30 points.