Anthony Ramnauth

Anthony Ramnauth

@philoneurosci.bsky.social

Postdoc - https://bsky.app/profile/lukesjulson.bsky.social @ Albert Einstein College of Medicine | Ph.D. JHU SOM - https://bsky.app/profile/martinowk.bsky.social @ LIBD.

503 followers952 following523 posts

Anthony Ramnauth reposted

Anjiolina Nakaya
@anjiolina.bsky.social

How come people in BlueSky don't talk about what has been happening in Indonesia for months now?! More than 300k people have acute respiratory infections. The haze even reached my city in the Philippines. That's how terrible it is. www.bbc.com/news/videos/...

bbc.com'Nowhere to escape' - Indonesians share footage of orange haze blanketing townsThick orange smog descended on the Indonesian city of Palangka Raya as wildfires continue raging nearby.

Anthony Ramnauth reposted

Patricia Gerdes
@pgerdes.bsky.social

I’m very happy to share that part of my postdoc work is now out in Science Advances! We find that a chimp-specific endogenous retrovirus (PTERV1) insertion silences LINC00662 and that silencing this lncRNA alters neuronal maturation in neural organoids 🧬🧠🐒 1/6 www.science.org/doi/10.1126/...

science.orgRetroviral insertions contributed to the divergence of human and chimpanzee brainsOver the past 5 to 7 million years, humans and chimpanzees have diverged in brain size, structure, and cognition despite high conservation of protein-coding genes. However, retroviral infections withi...

Anthony Ramnauth reposted

Anjiolina Nakaya
@anjiolina.bsky.social

I placed the Mata Asia's link on my profile. Please support the younger generation in educating and advocating for digital freedom. We also have professionals and experts with us. 💖 Much appreciated y'all

Anthony Ramnauth reposted

Malu Murugan
@malu-murugan.bsky.social

Many decades ago Olds and Milner found lateral septum stimulation to be extremely reinforcing. In our latest preprint we explore why. Check it out and let us know what you think www.biorxiv.org/content/10.6...

biorxiv.orgProjection populations form a dorsoventral gradient of reward representations in the lateral septumSeveral decades ago, the septal region was identified as the most dependable location of intracranial self-stimulation (ICSS) in the brain, but the neural substrates that mediate septal self-stimulation are still unknown. One part of the septal region, the lateral septum (LS), contributes to a number of motivated behaviors and may promote reward-seeking. However, the LS contains different anatomical subregions, complicating the characterization of its reward representations. We examine the responses of LS neurons along its dorsoventral axis using cellular resolution calcium imaging during an operant assay. We find that a greater proportion of neurons are excited in response to sucrose reward in the dorsal LS, while a greater proportion are inhibited in response to sucrose reward in the ventral LS. Additionally, we identify two distinct LS projection populations, one to the nucleus accumbens (NAc) and another to the bed nucleus of the stria terminalis (BNST), which are located in the dorsal and ventral regions of the LS, respectively. These two projection populations also have opposing reward responses and their corresponding optogenetic manipulation supports ICSS. These findings demonstrate how LS projection populations contribute to its functional heterogeneity, especially as it pertains to reward-seeking behavior. ### Competing Interest Statement The authors have declared no competing interest. National Institutes of Health, https://ror.org/01cwqze88, R01MH130755, F31MH133373 Alfred P. Sloan Foundation, https://ror.org/052csg198
Anthony Ramnauth
@philoneurosci.bsky.social

"Cells have split, merged, grown, and evolved... modern cells are the result of 4 billion years of continuous autopoietic history... each cell on Earth has been functional for several billion years, with... no interruption of its self-sustaining nature..." -Romain Brette The Brain, in Theory

Anthony Ramnauth
@philoneurosci.bsky.social

"Evolution alters living organizations by modifying proteins, acquiring new ones, changing developmental processes and occasionally merging different living forms. It does not directly tune biological structures." -Romain Brette The Brain, in Theory

Anthony Ramnauth reposted

Scientific American
@sciam.bsky.social

The National Science Foundation, one of the largest funders of research in the U.S., has been rocked by firings and budget cuts during the second Trump administration. Now, it is reportedly set to lose its leader at the end of the year sciam.com/article/nati...

sciam.comNational Science Foundation leader Brian Stone to retire with no clear replacement in sightPresident Donald Trump's nominee to replace Stone, James O'Neill, has yet to have a confirmation hearing in the senate, leaving the future leadership of the NSF unclear
Anthony Ramnauth
@philoneurosci.bsky.social

Perhaps it's because I came to neuroscience from philosophy, but I see that many neuroscientists see consciousness as a substance, state, process, etc., a singular property. However, I've always suspected the late Daniel Dennett might have been correct to call it a bag of tricks.

Anthony Ramnauth reposted

Mary Beth Hatten
@mbhatten.bsky.social

Congratulations on this important study!

Cerebellum Science Center@cerebellumcenter.bsky.social

The cerebellum isn’t just about movement; it gates social communication! Huge congrats to Dr. Cheryl Brandenburg (Sillitoe Lab), who led this work with her creativity and determination. We can’t wait to see where she takes this research in her own lab @lsu.bsky.social #neuroskyence tinyurl.com/CBSCO

tinyurl.comFrequency-dependent cerebellar circuits independently gate social vocalizations and movementBiological sciences; Behavioral neuroscience

Anthony Ramnauth reposted

Hillary Rodham Clinton
@hillaryclinton.bsky.social

Replying to @hillaryclinton.bsky.social

Now, Putin has proposed a summit with Trump and Xi to decide Ukraine’s fate for them, bulldoze a century of international cooperation, and frame Russia as an equal to the U.S. and China. We’ll see if Putin’s puppet continues to dance on his strings.

Anthony Ramnauth reposted

Richard Sever
@richardsever.bsky.social

"Because manuscripts reflected real progress towards our field’s goals, our assessment systems began relying on them as primary metrics...which is obviously flawed...Generative AI has broken this already-flawed proxy completely" journals.plos.org/plosbiology/...

journals.plos.orgWhat is biology research for?In the age of generative artificial intelligence (AI), the assumption that writing a paper requires doing science no longer holds true. Before deciding how to respond to the surge of AI-generated pape...

Anthony Ramnauth reposted

The Economist
@economist.com

In “Blockers”, Michael Lewis tells the stories of federal workers who tried to resist Donald Trump’s assault on the bureaucracy. Register for free to read our review bit.ly/4hXuMXf Photo: Tierney L. Cross/The New York Times/Redux/eyevine

Anthony Ramnauth reposted

Annika Barber
@annikabarber.bsky.social

Admin cries poverty while we negotiate a union contract asking for job security, improvements in campus infrastructure, financial investment in research and teaching...but somehow there's money for dystopia.

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Anthony Ramnauth reposted

Stephanie L. Grella, PhD
@sgrella.bsky.social

Our paper is out! link.springer.com/article/10.1...

link.springer.comChemogenetic inhibition of the ventrolateral orbitofrontal cortex disrupts novelty-guided updating of spatial memories and alters hippocampal engram reactivation - PsychopharmacologyRationale Adaptive behavior requires revising memories when outcomes deviate from expectations. The orbitofrontal cortex (OFC) is implicated in representing outcome expectancies, but its role in memor...

Anthony Ramnauth reposted

Science Magazine
@science.org

New research finds the world’s once-largest penguin colony is in perilous decline. Climate change appears to have made food scarce for these chinstrap penguins, which had numbered more than 1 million on a remote South Atlantic island. Learn more: https://scim.ag/4yDy1KH

Anthony Ramnauth reposted

Nick Miroff
@nickmiroff.bsky.social

NEW: ICE is trying to deport a mother of 4 while her husband is at Fort Benning in Army basic training. When she went to pick up the family's military IDs, Navy personnel turned her over to ICE. She's been in the US since age six. With @nancyayoussef.bsky.social www.theatlantic.com/politics/202...

theatlantic.comHe Joined the Military. They Reported His Wife to ICE.When a soldier’s wife went to pick up her military ID at a base in Texas, ICE officers showed up.

Anthony Ramnauth reposted

Kerri Smith
@kerri-smith.bsky.social

Why not be a protein-coding RNA and also regulate some gene expression on the side?

Philip Ball@philipcball.bsky.social

This is a truly startling paper. It shows that mRNA can perform regulatory functions *in addition to* its role in encoding a protein. In other words, the distinction between protein-coding RNA and noncoding regulatory RNA is fuzzy. /1 www.science.org/doi/10.1126/...

science.orgRegulation of target gene expression by chromatin-associated protein-coding transcripts in plantsProtein-coding transcripts are regarded as intermediates that mediate DNA-to-protein information flow, leaving their noncoding regulatory potential largely underappreciated. Genome-wide profiling of R...

Anthony Ramnauth reposted

Ashley Juavinett, PhD
@ashleyjuavinett.bsky.social

Fantastic work by this @ucsandiego.bsky.social crew

Takaki Komiyama @takakikomiyama.bsky.social

Our paper is out in Nature, congrats to Qiyu, An et al! By stimulating ~20 motor cortex neurons carefully selected based on their activity, we could induce learned population activity and, sometimes, the movement itself, depending on the brain's state. www.nature.com/articles/s41...

nature.comTargeted stimulation of motor cortex ensembles drives learned movements - NatureOptogenetic stimulation of motor-cortex neuron ensembles shows that precisely timed activity in the primary motor cortex can generate learned neural patterns and movements, demonstrating an active rol...

Anthony Ramnauth reposted

Daniel Bellingradt
@dbellingradt.bsky.social

Scientists who made their ideas by using a commercially AI-tool worry that AI is stealing their ideas …

Jennifer Ouellette@jenlucpiquant.bsky.social

Scientists worry AI is stealing their ideas www.scientificamerican.com/article/scie...

scientificamerican.comScientists worry AI is stealing their ideasResearchers are using AI as a sounding board throughout their work. But concerns are growing that companies may present users’ ideas as those of their models

Anthony Ramnauth reposted

Navin Pokala 🇺🇸🇺🇦🇨🇦🇬🇱
@navinpokala.bsky.social

Why do we need a Turing test for fascists? If someone’s words and/or actions are indistinguishable from a fascist, then they are fascist.

The Atlantic@theatlantic.com

Does Megyn Kelly, the TV host turned YouTube polemicist, really believe what she’s saying? @sophiegilbert.bsky.social asks. She spent a week watching Kelly’s show to find out:

bit.lyMegyn Kelly’s Extreme MakeoverDoes the TV host turned YouTube polemicist really believe what she’s saying?
Anthony Ramnauth
@philoneurosci.bsky.social

#Orbitofrontal value dynamics and #striatal population #geometry during interruption of automatic #behavior: Neuron www.cell.com/neuron/fullt...

cell.comOrbitofrontal value dynamics and striatal population geometry during interruption of automatic behaviorElston and Wallis examined how monkeys use cognitive control to override automatic behavior. Cognitive conflict made OFC value representations volatile and increased oscillatory synchronization with t...

Anthony Ramnauth reposted

Joshua Weitz
@joshuasweitz.bsky.social

The NIH proposal to conceal reviewer scores from program officers, investigators, and advisory councils is ill-conceived, introduces disproportionate weight to small percentile differences, diminishes the role of scientific peer review, and should be withdrawn in its entirety. a 🧵

joshuasweitz.substack.comWhat is NIH Leadership Trying to Hide from Researchers & the Public?A NIH proposal to conceal reviewer rankings of investigator-initiated research grants is ripe for misuse & demands a collective response (by October 13).

Anthony Ramnauth reposted

Princess Vimentin PhD | Cancer Biologist
@princess-vimentin.bsky.social

In 2021, researchers used optogenetic therapy to partially restore sight in a blind man. They used light to turn nerve cells on & off. A clinical trial shows promise. It is the basis of the 2026 Nobel Prize in Medicine. A breakthrough yrs in the making. 🧪 www.theguardian.com/society/2026...

theguardian.comGene therapy can partly restore sight in blind people, researchers revealOptogenetic therapy, based on Nobel prize-winning science, involves turning nerve cells on and off using light