Pablo J. Sáez

#HappyNewYear ! Let's start 2026 with a @cellcommlab.bsky.social paper How many branches is OK during #CellMigration? It depends on the #cell: for ex. immune cells are just fine. In collab. w. #NirGov @hfspo.bsky.social Full www.science.org/doi/10.1126/... @focalplane.bsky.social @science.org 🧪🔬

Cell division for this fluorescence Friday. Mitochondria are blue, actin is orange.

Call for a group leader in Evolutionary Biology The IGFL @igflyon.bsky.social in Lyon, France, is recruiting a group leader in Evolutionary Biology. An exciting place for exploring the interfaces of evolution with physiology and development. #EvolBiol #ecoevo #evodevo tinyurl.com/evolbiol

Can protecting the cell nucleus prevent heart failure—even when the genetic defect remains? Our new study in @CircRes suggests it can! We identify nuclear envelope rupture as a key driver of LMNA-related cardiomyopathy. 1/7 doi.org/10.1161/CIRC... #Mechanobiology, #lamins, #LMNA

ECRs - last few days to apply for a funded place at our Workshop on Bridging Scales and Disciplines to Understand Robust Development, 18-21 April 2027, organised by Mauricio Rocha Martins @rocha-lab.bsky.social and Giulia Paci @giuliapaci.bsky.social Apply at www.biologists.com/workshops/ap...

We are hiring an AI@HHMI Program Manager to help run HHMI's $500M AI initiative: projects, budgets, staffing, recruiting, events, outreach. Advanced degree, program management experience, fluent with AI tools and effective without them 😉. Work with me! hhmi.wd1.myworkdayjobs.com/en-US/Extern...

Immune cells don't only interact with the ECM, they also interact with surrounding cells in tissue as they migrate. This video gives me so much joy because there is just so much biology here to be discovered. Sticky cells! Here, immune cells are 🔴, ectodermal cells are ⚪. Happy #FluorescenceFriday

Intrinsic3D, a new imaging approach that allows researchers to image entire cells + tissues in 3D at single-molecule resolution, making large-volume super-resolution imaging faster & easier. @kanishka03.bsky.social covers work #StJohnstonLab - #preLight ⬇️ prelights.biologists.com/highlights/f...

Tomorrow, new MSc students start their program I'll make them play the classic "spot the differences"👇🏽, bc The North remembers...& The Mad Microscopy Gang #TMMG too I'll try to follow @cilialab.bsky.social & @aaandmoore.bsky.social to keep my chill & not start ranting #microscopy #AI #AIslop🧪🔬

We are updating our Expansion Microscopy (U-ExM) website with : - Protocols tips to help you get started - Examples of applications across different biological systems. - work in progress - an antibody database 👉 mocel.unige.ch/research-gro...

Have you ever wondered how cells in developing embryos manage to squeeze through tiny spaces? And how do they cope with mechanical stresses imposed by surrounding tissues? Check out our paper, now out @natcellbio.nature.com : www.nature.com/articles/s41...

I like it- Mad Microscopy Gang- should it be our sign-off for the letter... If you want to stop the #AISlop in microscopy, still time to sign up here forms.gle/TyGRELnCxq5z...

I managed to show it in my departmental seminar just on time before they deleted it. The only problem is that I wanted to show "the hallucination rendition" to my students on Monday. Does anyone still have that "microscopy" movie ?

🔬 We're hiring a Laboratory Manager! Join our growing international team at the Max Planck Center for Physics and Medicine in Erlangen! 🧬 Cell & molecular biology 🧪 Lab coordination & experimental research 📩 Apply now: [https://www.fau-jobs.de/jobposting/8173a98034c48d53d57bce14503883cbdbf6f3b80]

🧪 Considering an HFSP Research Grant? Join our webinar on the 2028 call for application guidance and a live Q&A! 📅 17 Nov | Two sessions: 🕘 09:00 CET 🕓 16:00 CET 🔗 Register: zurl.co/qHCzP #HFSP #FrontierScience #sts

Researchers from cilia biology and microscopy, as well as primary ciliary dyskinesia clinicians, have written an open letter to Nikon regarding the winning video in their Small World in Motion competition. To read the open letter and find out how to add you name:

#CellMigration meets #Cilia In our recent FocalPlane features… cell migration webinar, @raphclement.bsky.social treated us to a beautiful talk showing how Trichoplax use cilia polarisation to navigate without neurons or muscles. View the full recording: focalplane.biologists.com/2026/09/25/f...

None of this year's science Nobel Prizes have gone to women. The number of these prizes to go to women remains at 27 out of more than 600. See how many you can name in our quiz: www.nature.com/immersive/d4...

📣Our department is hiring a new group leader!📣 Want to start your team in a vibrant scientific environment in the center of Paris? I was very lucky to do that 10 years ago, reach out if you have any question. Apply by December 18th: jpi-recruitment-curie-umr3215-u934.curie.fr

BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”

Looking for a PhD? @crick.ac.uk PhD applications for next year are open. 4 year program with lots of outstanding projects on offer. If you are interested in viral host interactions, cytoskeleton, cell bio, live cell imaging - see Way lab project + video. plz repost www.crick.ac.uk/careers-and-...

Happy #FluorescenceFriday. Single immune cell migration is fascinating. But these cells can also behave like a coordinated collective, like 🐝 from a hive. I captured some embryonic myeloid cells (🔴) displaying swarming behaviour in a migrating ectoderm cell sheet (🔵), like neutrophils in our body!

🚨PREPRINT ALERT How different are males and females? In physiology we mostly treat that as a fixed property of a species, something to control for. In mice, we found it is not fixed at all. It depends on what the animal ate while growing up.

Call for abstracts: the UK Cell Motility Club is back! Keynote speaker : Caren Norden 🐠 Fantastic early career talk opportunity and lovely community! Register here: forms.cloud.microsoft/e/zNNCMfD5jF

While we’ve heard that watching cell blebs (like watching larva lamps) can be relaxing, we think that @ankita13jha.bsky.social’s talk from our #CellMigration webinar will leave you feeling excited about #science & running to your #microscope! Full video @ focalplane.biologists.com/2026/09/25/f...

Happy to see the peer-reviewed version of SpaCEy now out: 📄 Published paper: www.nature.com/articles/s41... 💻 Code: github.com/saezlab/SpaCEy

Are you looking for a postdoc exploring the cell biology of development, defining how cells change shape and move? Do you want to develop a research program & teaching skills preparing you for a position at a college or small University? Our new NIH grant will support those goals 1/n Please share

What a fantastic visitor! Thanks Pablo @pjsaez.bsky.social @cellcommlab.bsky.social for visiting Turku (organised by @mattilalab.bsky.social )! Especially, it was a pleasure to hear your experiences and thoughts during the career/science session. Thanks for taking the time and sharing your opinion!

ICYMI: the recording of our second webinar on emergent models and quantitative analysis of cell migration is now available. 🔬🎥Check it out to see talks from @ankita13jha.bsky.social, @raphclement.bsky.social and @katrinavelle.bsky.social focalplane.biologists.com/2026/09/25/f...

In @pcusachs.bsky.social’s lab at @ibecbarcelona.eu we have a fully founded open PhD position! It’s a very nice working environment & can promise cool mechanobiology🔬🧫 Here all the info ibecbarcelona.eu/predoctoral-...

Looking for a faculty position combining research in fundamental cell and molecular biology with therapeutic discovery? Join our amazing faculty at the @weillinstitute.bsky.social at Cornell University in Ithaca, New York. academicjobsonline.org/ajo/jobs/32657 Apply by Nov. 15! Please share!

#CellCommunication + #CalciumSignaling What else can you ask for?

#Mechanobiology rules! Today, it's not only Chile's independence day🇨🇱😋 ...but also Sara Wickström @sarawickstrom.bsky.social is getting the Körber Prize 👏🏽👏🏽👏🏽 for being a "curiosity's junkie" 😂 Of note, Kate photobombing is top @katemiro.bsky.social @focalplane.bsky.social @koerber-ip.bsky.social

Wanna see blebs dancing & new models of #CellMigration? Join us tomorrow to see the great talks from @ankita13jha.bsky.social, @raphclement.bsky.social & @katrinavelle.bsky.social Thu 17 Sep. at 15:00 BST / 16:00 CEST Register: focalplane.biologists.com/2026/09/03/f... @focalplane.bsky.social

Don’t miss the second webinar in our new series on cell migration, featuring talks from @ankita13jha.bsky.social, @raphclement.bsky.social and @katrinavelle.bsky.social. 🗓️Thursday 17 September at 15:00 BST For more info and to register: focalplane.biologists.com/2026/09/03/f...

Working on #cellmigration? Join us online tomorrow for the second webinar in our series, hosted by @pjsaez.bsky.social and @valeriaventurini.bsky.social

Relieved to remember that after 1 M versions + last minute changes somehow, somewhere there is light @ the end of the tunnel... Grateful for the work of my @cellcommlab.bsky.social Whenever is ready we'll post it to receive comments from the community 😉 Tks 4 existing @biorxivpreprint.bsky.social 🧪🔬

Gourkanti et al. @neal-lab.bsky.social show that the rhomboid protease Rhbdl2 restrains #macrophage recruitment & wound repair in #zebrafish, positioning Rhbdl2 as a potential brake on macrophage-driven repair rupress.org/jcb/article/... #Migration #motility #Immunology

‼️ Postdoc position open. We study how protein metabolism controls time. If you’re excited by this question, we’d love to hear from you! We’re looking for a motivated & collaborative researcher with a strong track record. 📅 30 September 2026 📢 Please share Apply here 👇👇

📢One week to go! Join us on Thursday 17 September at 15:00 BST (UTC+1) for our webinar on new models for studying cell migration, hosted by @pjsaez.bsky.social & @valeriaventurini.bsky.social. You’ll hear talks from @ankita13jha.bsky.social, @raphclement.bsky.social and @katrinavelle.bsky.social.

We are hiring! Start at a #MaxPlanckInstitute with your own independent Max Planck Research Group. This position is equivalent to a W2 Professorship at a German university, or Associate Professor internationally. 🔗Apply until October 14th! www.mpg.de/career/max-p... #ScienceCareer #MPRG #TenureTrack

LAST CALL FOR POSTER ABSTRACTS! We are just over 2 weeks away from the 2026 Triangle Cytoskeleton Meeting at the William and Ida Friday Center on Sept. 21st. Submit your abstract by Monday, Sept. 7th for the opportunity to present a poster. Registrations will remain open until Sept. 14th.

Very happy to share my postdoc paper is out now in @natcellbio.nature.com titled "Tissue flow acts as a guidance cue for immune cell polarization and directional migration". If you love imaging and immune cells, this is for you! #microscopymonday www.nature.com/articles/s41... A 🧵: 1/n

Even with all the advancements in automated cell tracking getting us to 90%+ accuracy...that's still a lot of broken tracks over long movies! Our brains are pretty good at this so I made Vizsla 🐕, a little @napari.org plugin, to help you fix your tracks manually. 👉 pypi.org/project/napa...

This is why we love #CellMigratuon ! This beautiful story is now out, very interesting role for RhoA and also the cover, Neutrophils on the 'Rho'ad Congrats to all authors, especially to former colleagues and friends Full @science.org www.science.org/doi/10.1126/...

I'm very excited to be included in this lineup! Thanks @pjsaez.bsky.social and @valeriaventurini.bsky.social for organizing!

We are excited to invite you to the second webinar in our cell migration series. In this webinar, we focus on new models for studying cell migration with talks from @ankita13jha.bsky.social, @raphclement.bsky.social & @katrinavelle.bsky.social. More info⤵️: focalplane.biologists.com/2026/09/03/f...

Another year is gone & I grow old and proud of the work of my team @cellcommlab.bsky.social To celebrate the 6th labversary, we did the best we can do: we submitted...now to cross fingers & to press F5. OK, to celebrate we also had pizza as tradition dictates ;) #CellMigration & pizza lovers 🧪🔬

Blebbing cell under confinement?

Hope you enjoy this short piece, which came out yesterday. Some thoughts I’ve been musing on for a while about why adaptive immunity evolved. Read it for free at rdcu.be/fAO5P

For @science.org , I wrote about brain-eating amoeba 🦠 and fascinating new research led by @katrinavelle.bsky.social which could help explain how the usually harmless pond-dweller ends up in the brain. www.science.org/content/arti...