Rahul K

Rahul K

@theresearch.bsky.social

I run, ski, and engineer cells and materials; asking how nutrient sensing & signaling work: bit.ly/RK-GoogleScholar TalTech| Ex: Tartu Ülikool; Karolinska Institutet, Chalmers; Kyutech; IITD

2K followers647 following404 posts

Rahul K
@theresearch.bsky.social

On the way to @leibnizinm.bsky.social organized 5th Engineered Living Materials 2026 conference in Saarbrücken, Germany. 🧪 Hello to fellow #ELMs researchers and please use #INM-ELM2026 | #ELM2026 hastags if post here. I'll present our research on metabolically active living materials [ #MALMs ].

Rahul K reposted

Ylva Ivarsson
@ivarssonlab.bsky.social

To all random people: No is the answer. I do not respond to unsolicited AI-generated emails about PhD opportunities. All PhD positions at UU are advertised on the university's website, and applications should be submitted through the official recruitment process. Stop wasting time and energy.

Rahul K reposted

Nature Nanotechnology
@natnano.nature.com

New Comment: NanostarDB: an interactive knowledgebase for standardized annotation, discovery, and reuse of nucleic acid nanostructure designs. nature.com/articles/s41... #DNA #RNA #Nanotechnology

nature.comNanostarDB: an interactive knowledgebase for standardized annotation, discovery and reuse of nucleic acid nanostructure designs - Nature NanotechnologyThe lack of standardized reporting and annotation of nucleic acid nanostructures limits reproducibility, interoperability and the efficient reuse of published designs. NanostarDB is a community-driven...

Rahul K reposted

Vivek Mutalik
@vivekmutalik.bsky.social

🤯😮🤯 Systematic survey of “Noncodome”

bioRxiv Genomics@biorxiv-genomic.bsky.social

Systematic mapping of the prokaryotic noncoding sequence space with a genomic language model https://www.biorxiv.org/content/10.64898/2026.10.21.760802v1

Rahul K reposted

Nobel Prize
@nobelprize.org

Join us on 9 December in Stockholm, when we'll be discussing 'Life with AI' with AI experts and Nobel Prize laureates Philippe Aghion, Steven Chu, John Jumper and David MacMillan. Find out more about this year's Nobel Week Dialogue and sign up now at nobelprize.org/life-with-ai

Rahul K reposted

David Vilchez
@thevilchezlab.bsky.social

1/7 ❄️ Very happy to share our new study: “Cold activates a BH2 metabolic network promoting longevity and proteostasis.” nature.com/articles/s41... #Aging #Longevity #Proteostasis #Metabolism #ALS #HuntingtonsDisease

nature.comCold activates a BH2 metabolic network promoting longevity and proteostasis - NatureA multi-tissue signalling system links cold temperature to enhanced longevity and proteostasis in Caenorhabditis elegans.

Rahul K reposted

Nature Biotechnology
@natbiotech.nature.com

Deep dynamical models of single-cell multiomic velocities predict loss-of-function and rescue perturbations in B cells - @darkobar.bsky.social @weillcornell.bsky.social @mskcancercenter.bsky.social www.nature.com/articles/s41...

nature.comDeep dynamical models of single-cell multiomic velocities predict loss-of-function and rescue perturbations in B cells - Nature BiotechnologyDynaVelo integrates single-cell omics data to infer cell state dynamics and regulatory interactions.

Rahul K reposted

Eddie Rollins
@eddierollins.bsky.social

New preprint 🎉 afMLevel: Deep learning U-Net Models for Levelling Atomic Force Microscopy Images and Movie www.biorxiv.org/content/10.6...

biorxiv.orgafMLevel: Deep learning U-Net Models for Levelling Atomic Force Microscopy Images and MoviesAFM experiments can now produce hundreds of frames per session and this rises to thousands in the case of video-rate high-speed AFM, but every image must still be levelled to remove tilt, bowing and l...

Rahul K reposted

Aditya Kunjapur
@kunjapur.bsky.social

This work led by @jennbrophy.bsky.social and her lead student Vivian in collaboration with my lab & lead student Michaela published online this morning at Nature Biotechnology www.nature.com/articles/s41... Helps limit engr'd microbial functions to target plants Exciting science & amazing collab

nature.comGenetic code expansion enables plant-directed control of bacterial activity - Nature BiotechnologyThe noncanonical amino acid O-methyl-L-tyrosine is used as a tool to control microbial protein synthesis across diverse plants.
Jenn Brophy@jennbrophy.bsky.social

We engineer both plants and bacteria to establish non-standard amino acids as a new molecular language for programming plant-microbe interactions. This work contributes to the growing toolkit for precision agriculture and we hope it accelerates the path to a sustainable future!

Rahul K reposted

Richard Sever
@richardsever.bsky.social

How we are approaching AI at openRxiv - new blog post prompted by growing adoption by researchers, submission patterns, and questions from the community openrxiv.org/approach-to-... 1/n

openrxiv.orgHow we’re approaching AI at bioRxiv and medRxiv - openRxivWe have always run bioRxiv and medRxiv in service of researchers, aiming to share and disseminate research responsibly. Our policies and procedures have been developed in coordination with the researc...

Rahul K reposted

Frances Yap
@ribo1214.bsky.social

Visualization of co-transcriptional binding of an E. coli rRNA methyltransferase RsmB and importance of rsmB in cellular fitness. #RNASky www.science.org/doi/10.1126/...

science.orgMethyltransferase RsmB chaperones E. coli ribosome assembly by orchestrating the recruitment of ribosomal proteinsRibosomal RNA modification enzymes increase cellular fitness, but it’s little known whether this benefit arises from rRNA modification or a chaperone function of the modification enzyme. Here, we show...

Rahul K reposted

David Suter
@davidsuter.bsky.social

IMO the paper of the year in the gene regulation field - such a clean and clear study, showing how promoter-enhancer contacts mediate transcriptional activation. www.cell.com/cell/abstrac...

cell.comMechanisms of transcription control by distal enhancers from single-gene nanoscopyHigh-resolution real-time imaging of enhancer-promoter communication reveals how the two genomic loci are actively brought together through cohesin-mediated loop extrusion and how E-P interactions are...

Rahul K reposted

Will Ratcliff
@wcratcliff.bsky.social

1/ How do cells divide when they're stuck in something squishy? Most of what we know about the cell cycle comes from yeast in liquid or on flat plates, but in nature they live in dough, mucus, soil and tissue. This new paper asks what that does to division. Love this one!

Rahul K reposted

Sorek Lab
@soreklab.bsky.social

Very nice discovery from the Jackson, Bravo and Basel labs. Cleaved tRNA ends, loaded with an amino acid, activate a form of bacterial immunity

bioRxiv Microbiology@biorxiv-microbiol.bsky.social

Aminoacylated tRNA tails trigger auxiliary bacterial immunity https://www.biorxiv.org/content/10.64898/2026.10.14.759216v1

Rahul K reposted

Max Spicer
@mfdspicer.bsky.social

Our paper on apoptotic chromatin compaction is out now! Take a look in @embojournal.org, where we investigate compaction in living and dying cells, and show that histone deacetylation prevents DNA from spilling into extracellular vesicles in apoptosis @gerlichlab.bsky.social @imbavienna.bsky.social

The EMBO Journal@embojournal.org

How does DNA remain confined to dying cells despite its fragmentation? @mfdspicer.bsky.social @rcollepardo.bsky.social @gerlichlab.bsky.social et al show histone deacetylation compacts apoptotic chromatin, preventing it from entering apoptotic extracellular vesicles link.springer.com/article/10.1...

link.springer.comElectrostatic control of chromatin compaction safeguards against apoptotic DNA release - The EMBO JournalApoptosis involves extensive intracellular reorganisation to facilitate the clearance of dying cells. A key step in this process is the destruction of the genome through fragmentation by caspase-activ...

Rahul K reposted

Megan Bergkessel
@slowgoing.bsky.social

Congratulations to the authors on this very comprehensive study of protein turnover during starvation in E. coli! Definitely worth a read if you care about bacteria living outside of steady state exponential growth (and you should!)

Cameron Thrash@jcamthrash.bsky.social

Global proteolysis during starvation governs proteome remodeling and a survival–regrowth trade-off in bacteria www.pnas.org/doi/abs/10.1... #jcampubs

pnas.orgGlobal proteolysis during starvation governs proteome remodeling and a survival–regrowth trade-off in bacteria | PNASStarving bacteria must synthesize stress proteins to survive, but how protein synthesis persists in the absence of nutrient influx is unclear. We s...

Rahul K reposted

LSE Impact
@lseimpactblog.bsky.social

🗣️"Networks help ideas travel before they become publications. They allow a draft to be challenged, a method to be improved, a policy question to be sharpened and a young researcher to learn the unwritten rules of scholarly communication." #ECRchat #ResarchNetworks

blogs.lse.ac.ukFrom open access to open participation, why research impact starts before publication - LSE ImpactIf open research is judged only by who can read the final article, it overlooks who has the networks, feedback and institutional support to shape research.

Rahul K reposted

The Braun Lab
@thebraunlab.bsky.social

Now published in Nature Communications! 🎉 www.nature.com/articles/s41... Subtelomeric heterochromatin is organized into distinct subdomains with different epigenetic stability and recovery properties. And there's quite a bit of new data since the preprint! New experiments show that.... (1/3)

nature.comDiscrete subdomains establish epigenetic diversity in subtelomeric heterochromatin in fission yeast - Nature CommunicationsHere the authors show that subtelomeric heterochromatin in S. pombe forms a mosaic of subdomains with distinct requirements for gene silencing and different epigenetic stability, ranging from highly f...
The Braun Lab@thebraunlab.bsky.social

This one feels special: our latest work on subtelomeric heterochromatin is now on www.biorxiv.org/content/10.1.... This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.

biorxiv.orgDiscrete Subdomains Establish Epigenetic Diversity in Subtelomeric HeterochromatinSubtelomeres are imperfect repeats adjacent to telomeres that are repressed by heterochromatin. Although essential for genome integrity, their repetitive nature has thwarted dissection of local hetero...

Rahul K reposted

Matthew Alexander, PhD
@mattmuscleguy.bsky.social

New #Cell_Metabolism paper: An NAD+-responsive adipose signal coordinates inter-organ defense against muscle atrophy. #Myoblue tinyurl.com/368227ux

tinyurl.comAn NAD+-responsive adipose signal coordinates inter-organ defense against muscle atrophyLiang et al. identify an NAD+-responsive adipokine Serpina3n that protects skeletal muscle against aging- and disease-associated atrophy. NAD+ elevation promotes adipose Serpina3n production through S...

Rahul K reposted

andreabelluati.bsky.social
@andreabelluati.bsky.social

My Perspective is out in JACS Au! “The Xenoreactome: Where Foreign Chemistry Becomes Biological Organization” It grew from a question I've had since my PhD: what happens when biology performs chemistry it never evolved to perform? doi.org/10.1021/jacs...

doi.orgThe Xenoreactome: Where Foreign Chemistry Becomes Biological OrganizationAbstract. Biological systems can perform chemistry beyond their evolved reaction networks, but a reaction that is chemically possible does not necessarily

Rahul K reposted

Biointegrated Photonics Lab
@schubertlab.bsky.social

Happy to share our new publication on liquid crystal #microlasers. We show that bipolar spheres confine light in only a single plane. Interestingly, the bipolar refractive index profile also induces a splitting of the whispering gallery modes. Why? Check-out the paper to find out! #WGM #research

advanced.onlinelibrary.wiley.comPurely Equatorial Lasing in Spherical Liquid Crystal Polymer Microlasers with Bipolar Refractive Index ProfileSpherical liquid crystal polymer microlasers with a bipolar configuration confine lasing to a single equatorial plane, allowing precise control over where the laser emission is generated. The anisotr...

Rahul K reposted

Dr Emma Hodcroft
@firefoxx66.bsky.social

There are some people you just feel better knowing that they're out there. Helen was one of those people. The outpouring among so many tonight, is testament to that. The world is a little emptier tonight without her. Thank you for everything @helenbranswell.bsky.social!

STAT@statnews.com

We are going to miss you very much, Helen. https://www.statnews.com/2026/10/13/helen-branswell-stat-reporter-obituary/

statnews.comHelen Branswell, whose reporting on infectious diseases and public health drew acclaim, dies at 69Helen Branswell, STAT's infectious disease reporter who earned the respect of experts and public health officials with her accessible, prescient dispatches, has died at age 69.

Rahul K reposted

Itai Yanai
@itaiyanai.bsky.social

1. It’s not what you had planned for the project? 2. It’s not the field you were trained in? 3. It’s not certain to work? In science, as in art, the trick is to be open to going wherever the project directs you.

Rahul K reposted

Di Jiang
@dijiang319.bsky.social

Last week @science.org A DNA Typewriter records the cell lineage history of a mouse, from zygote to late organogenesis | Science www.science.org/doi/10.1126/...

science.orgA DNA Typewriter records the cell lineage history of a mouse, from zygote to late organogenesisMammalian biology unfolds over time, within tissues and organs opaque to our eyes and instruments. We applied DNA Typewriter, a sequential molecular recorder, to record the cell lineage of a mouse ove...

Rahul K reposted

Verena Kohler
@verenakohler.bsky.social

Looking for a postdoc interested in ageing biology and proteostasis 📅 Deadline: Nov 15 More details in attached document #Postdoc #PostdocOpportunity #Proteostasis #LongevityResearch #AcademicJobs #ResearchJobs

Rahul K reposted

Nature Metabolism
@natmetabolism.nature.com
dlvr.itA multi-fluid exercise proteomic atlas reveals regulators of health and diseaseNature Metabolism, Published online: 12 October 2026; doi:10.1038/s42255-026-01642-5A single bout of exercise triggers thousands of coordinated protein changes across blood, saliva and urine. By integrating tissue atlases, human genetics and in vivo functional validation, we present a multi-fluid resource that serves as a starting point for prioritizing robust candidate exercise-regulated proteins that might mediate the cardiometabolic health benefits of long-term exercise.