Matt Rockman

Matt Rockman

@wormsrock.bsky.social

Evolutionary zoology & quantitative genetics Biology Professor, New York University

3K followers1.5K following202 posts

Here's something unusual: a polychaete larva with two tails? One episphere, three eyes instead of four, and two perfectly formed trunks. But alas, no mouth, so it can't feed. Its sibs have already metamorphosed. Spiralian dev biologists: how is this even possible?

Matt Rockman reposted

I’m looking to hire an NIH funded postdoc to join our lab here at Davis (please RT). Ongoing areas of interest include: 1) polygenic signals of selection from time series, ARGs, GWAS, etc 2) The interpretation of GWAS, polygenic scores, & sources of confounding

Matt Rockman reposted

Interesting sea cucumber with a collector's behavior! in the Atlantic, a similar genus, Oloughlinius does something with pteropod shells! 1365m North Tutuila Flank, american samoa

Matt Rockman reposted

Richaud et al. report loss-of-function alleles of the gtnt-1 orthologs are found at low frequency in C. elegans and C. briggsae, demonstrating repeated molecular evolution leading to parallel evolution of viral resistance. 🔗 academic.oup.com/mbe/article/... #societyjournal #celegans

academic.oup.comRepeated mutation of a GT92 glycosyltransferase gene confers antiviral resistance in two Caenorhabditis speciesAbstract. Host–pathogen interactions evolve rapidly within species, providing natural genetic resources for the identification of specific ecological inter

Matt Rockman reposted

Now out @molbioevol.bsky.socialGenetic correlations summarize how traits covary, but they can hide different underlying architectures. Distinguishing those architectures can reveal distinct mechanisms generating—and potentially constraining—trait–trait relationships. academic.oup.com/mbe/advance-...

academic.oup.comConsistent and idiosyncratic pleiotropy in shaping genetic correlationsAbstract. Pleiotropy, the phenomenon where a single mutation influences multiple phenotypic traits, creates genetic correlations that can constrain evoluti

Matt Rockman reposted

Skill issue

Dan Silverman@dmsilverman.bsky.social

New study shows that — contra widely accepted narratives — there is NO EVIDENCE that professors change their students’ politics and make them more liberal through their teaching

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I find this new discovery of a transmissible cancer in catfish fascinating. As it’s described as the fourth example of contagious cancer, let me share this phylogenetic tree of species infected by such rarities.

Nature@nature.com

Researchers have discovered a contagious cancer in catfish – just the fourth example of tumour cells that spread naturally from one animal to another go.nature.com/4fsoLR3

Matt Rockman reposted

Excited to announce that this fall I'm starting my lab at the University of South Carolina! Our hybrid wet/dry lab will explore fundamental topics in animal evolution, looking at how different evolutionary processes combine quantitatively [pleiotropic conflicts, mutation bias, etc.].

Matt Rockman reposted

I had a wonderful time at @northamptonshirenhs microscopy group meeting today, where I had the privilege of doing a presentation about marine plankton, and sharing a live sample with them! Here are some of the organisms we saw. #marineplankton 🦑

Matt Rockman reposted

Matt Rockman reposted

Matt Rockman reposted

Happy to highlight new findings by Vanesa Getseva and Lin Poyraz about the sources of variation in germline mutation rates among humans: www.biorxiv.org/content/10.6... Joint work with Anastasia Stolyarova and @ipsitaagarwal.bsky.social. 1/n

biorxiv.orgA sibling study of variation in parental mutation ratesPeople are born with variable numbers of de novo germline mutations (DNMs), depending primarily on the ages of their parents. To explore additional causes, we developed an approach to call DNMs from nucleotide differences between siblings in genomic regions inherited identical by descent from both parents. Applying it to whole genome sequences from 28,985 sibling pairs of diverse genetic ancestries present in the UK Biobank and All of Us datasets, as well as 2,330 trios, we identified >800K autosomal DNMs and characterized mutation phenotypes in 27,645 sets of parents. We found subtle shifts in the mutation spectrum but no differences in total DNM rates among genetic ancestry groups, or between smokers and non-smokers. Testing for associations between parental mutation phenotypes and their burden of loss-of-function and deleterious missense variants in a set of 180 DNA repair and maintenance genes, we discovered that disruptions in REV1 and LIG1 increase germline mutation rates, and thus that rare mutator alleles segregate in population cohorts. ### Competing Interest Statement The authors have declared no competing interest. NIH, R35 GM083098

Matt Rockman reposted

this is a great book — highly recommend it

Seth Rockman@sethrockman.bsky.social

Look what's here! Just in time to order for your fall classes! It's the affordable paperback version of *Plantation Goods* from @uchicagopress.bsky.social

Matt Rockman reposted

It's looking increasingly likely that I'll be hiring a 3-year computational pop-gen postdoc/PhD-level scientific programmer to start this Fall (2026). If you or someone you know is defending soon, and looking for a position, please DM/write to me! Thanks!

Matt Rockman reposted

Matt Rockman reposted

Matt Rockman reposted

I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.

Matt Rockman reposted